A newly discovered interference of the central nitrergic system on oxytocin-induced hypophagia in layer-type chickens
Journal Title: Iranian Journal of Veterinary Science and Technology (IJVST) - Year 2021, Vol 13, Issue 1
Abstract
Various neurochemical pathways are participating in the regulation of food intake in mammals and birds. Both oxytocin (OT) and nitric oxide (NO) are known as hypophagic agents in birds. This study consisted of 6 experiments and each experiment had 4 groups (ngroup=11, 5-day-old chickens). In all experiments, 3-hour food-deprived (FD3) birds received intracerebroventricular (ICV) injections either control diluent or drug solution. Then the birds had ad libitum access to the food and fresh water and then cumulative food intake (gr) was measured based on the percentage of the body weight (%BW). In experiments 1 to 3, ICV injections of L-arginine (precursor of NO, 200, 400, and 800 nmol), L-NAME (NOS inhibitor, 100, 200, and 400 nmol) and OT (2.5, 5, and 10 µg) were performed respectively. In experiment 4, each group received any ICV injections of L-NAME (100 nmol), OT (10 µg) or a co-injection of L-NAME (100 nmol) and OT (10 µg). In experiment 5, L-arginine (ICV, 200 nmol), OT (10 µg), or L-arginine (200 nmol) and OT (10 µg) were injected to the groups. Experiment 6 was similar to the experiment 5, although the dose of OT was 2.5 µg in all the treatment groups. Results showed that the ICV injection of L-NAME (100 nmol) significantly attenuated hypophagic effect induced by OT (10 µg) (p < 0.05). Findings suggested that NO might mediate the hypophagic effect of OT in FD3 neonatal layer-type chickens.
Authors and Affiliations
Morteza Zendehdel,Mina Khodadadi,Homeyra Zandiyeh,Kasra Mokhtarpouriani,Behrouz Rahmani,Ali Baghbanzadeh,
Production performance of kampung hens fed rations containing black soldier fly larvae powder
This research aimed to find a suitable formulation for rations containing Black soldier fly larvae powder to support the optimal kampung hen production performance. Four to five-month-old Kampung hens were given feed wit...
Occurrence, hematologic and serum biochemical characteristics of neonatal isoerythrolysis in Arabian horses of Iran
Neonatal isoerythrolysis is a major cause of anemia in newborn foals. However, there are no documented data regarding the occurrence of neonatal isoerythrolysis in Arabian horses of Iran, which are mostly raised in Khouz...
Relationships between trace elements, oxidative stress and subclinical ketosis during transition period in dairy cows
The possible relationships between trace elements, oxidative stress and subclinical ketosis during the transition period were evaluated in dairy cows. Blood samples were obtained by jugular venipuncture at four times o...
The Eff ect of resistance training and growth hormone injection on circulating IGF-1 and IGFBP-3 levels in a rat model
Growth hormone has mitotic and anti-apoptotic effects which may increase proliferation and transformation of cells when it is expressed aberrantly. This study investigated the effects of resistance training and growth...
Radiographic and histological evaluations of the effects of meloxicam and flunixin meglumine on the repair of radial bone defects in a rabbit model
The current study radiographically and histologically evaluated the effects of meloxicam and flunixin meglumine on the repair of radial bone defects in a rabbit model. Ninety New Zealand White rabbits (10-12 months, 1.5-...