A Novel SNP in the Coding Region of the Akirin2 Gene and Its Association with Marbling Score in Hanwoo (Korean Cattle)
Journal Title: Journal of Animal Science Advances - Year 2015, Vol 5, Issue 5
Abstract
The Akirin2 is a nuclear factor which plays important roles in immune response, skeletal myogenesis, muscle development and carcinogenesis. Interestingly, a specific SNP located in 3'-UTR region of Akirin2 gene has previously been found to be significantly associated with marbling in beef cattle. Thus, the Akirin2 gene was considered as a positional functional candidate gene for marbling. The objectives of this study were to identify SNPs in the exonic regions of the Akirin2 gene and to evaluate the association of these SNPs with carcass and meat quality traits in Hanwoo (Korean cattle). In this study, I newly identified one exonic SNP (g.6559T>C) located within exon 1 in Hanwoo population. Genotyping of the SNP marker was carried out using PCR-RFLP analysis in Hanwoo steers to evaluate association with carcass traits. As a result, g.6559T>C SNP genotype was significantly associated with effects on marbling score. TT homozygous genotype or TC heterozygous genotype had a significantly higher marbling score (p<0.004) than those with CC homozygous genotype. Additive genetic effect was also observed for the marbling score (P<0.01) with higher marbling score of homozygous animals. Results from this study suggest that the exonic SNP g.6559T>C in the Akirin2 gene may be used as a DNA marker for the selection of Hanwoo with higher marbling.
Authors and Affiliations
E. R. Chung
Keywords
Related Articles
- EP ID EP163598
- DOI -
- Views 138
- Downloads 0
The Efficacy of a Novel Microbial 6-phytase Expressed in Aspergillus Oryzae on the Performance and Phosphorus Utilization in Swine
Three studies were carried out to evaluate a novel microbial 6‑phytase, expressed via the use of synthetic genes in Aspergillus oryzae in weaned piglets and also in growing pigs. In the first study, the enzyme was fed to...
Estimation of Live Body Weight from Heart Girth, Body Length and Condition Score in Nilotic Cattle – Southern Sudan
Data obtained from livestock survey in Malakal area was used to determine the extent to which live body weight was related to heart girth, body length and condition score in Nilotic cattle. Body weight, heart girth and b...
Growth Performance, Carcass Characteristics and Cost Benefits of Four Broiler Strains on Restricted Feeding Regimen in North Central Nigeria
Growth performance and carcass quality of broilers irrespective of genetic standardization depend on feeding pattern. In order to determine the effect of feed restriction on broiler strains in north central Nigeria, 192...
Effect of Dry Neem Leaves (DNL) in the Reduction of Ammonia Level of Poultry Litter Compared to Biochemicals Amendment
An experiment was carried out on broiler litter by using dry neem leaves (DNL) and biochemical product to know their effect on the reduction of ammonia (NH3) level. Cobb 500 day old chicks were reared under semi environm...