A Novel Wrapper-filter Hybrid Method for Candidate SNPs Selection
Journal Title: IOSR Journals (IOSR Journal of Computer Engineering) - Year 2016, Vol 18, Issue 4
Abstract
Abstract: Genomic studies provide massive amount of data including thousands of Single Nucleotide Polymorphisms (SNPs). The analysis of SNPs helps to identify genetic variants related to complex traits. Therefore, it is essential to provide an efficient method to find a small subset of candidate SNPs as good representatives of the rest of SNPs.In this study, a new feature/SNP selection method based on the relationship between filter and wrapper criteria (i.e. correlation and model accuracy) is proposed. The method is based on the prediction of Mean Square Error (MSE) in terms of the number of features, Mean Feature-Feature Correlation (MFFC) and Mean Feature-Target Correlation (MFTC). It trains a Neural Network (NN) to predictthe accuracy in terms of the number of features, MFFC and MFTC.We ran experiments on artificial SNPs datasets, comparing our algorithm with well-known feature selection techniques, and obtained higher accuracy in selecting the candidate SNPs in shorter running time.
Authors and Affiliations
Farideh Halakou
Keywords
Related Articles
- EP ID EP101742
- DOI -
- Views 113
- Downloads 0
Video To Animated Cartoon Conversion
Abstract: the logic of animation making from real video fully depends on various image processing techniques and various kinds of filtering like Gaussian filtering, bilateral filtering, and flow based bilateral fil...
Internet Worm Classification and Detection using Data MiningTechniques
Abstract: Internet worm means separate malware computer programs that repeated itself and in order to spreadone computer to another computer. Malware includes computer viruses, worms, root kits, key loggers, Trojan...
Effective query processing techniques for heterogeneous application data
In the different application environment, in order to a chievea effective query processing result stechniques are required. This type of effective query processing result techniques are implementing in order to different...
Payment of Bus Fare Using Handy Card
Abstract: There are abundant people in day to day life travelling in either government bus or private bus. The foremost delinquent that the user faces is that they don’t get the remaining amount from the conductor that t...
Glaucoma Detection Using Enhanced K-Strange Points Clustering Algorithm and Classification
Glaucoma is an eye disorder that majorly affects the optic nerve head in the retina. The damage caused to optic disc leads to gradual loss of peripheral vision which may further result in complete blindness. Glaucoma can...