A Pharmacoepidemiological Study Of Ticagrelor & Current Antiplatelet Agents In Acute Coronary Syndrome (ACS) & Percutaneous Transluminal Coronary Angioplasty (PTCA)
Journal Title: Journal of Medical Science And clinical Research - Year 2014, Vol 2, Issue 6
Abstract
The incidence of ACS is rapidly increasing in India & causing high mortality. In the treatment pattern of ACS & PTCA, antiplatelet agents are prescribed as a part of maintenance & prophylactic therapy. Ticagrelor, a newer non-thienopyridine & first reversibly binding oral P2Y12 platelet inhibitor, provides faster, greater & more consistent platelet inhibition than clopidogrel. It is proved by the PLATO trials that it is more potent among anti platelet therapy used in ACS & PTCA patients. The utilization rate of various antiplatelet agents like Aspirin, Clopidogrel & Prasugrel compared to Ticagrelor in the common clinical practice was studied .The effect of contraindications, cost & Physician’s preference related aspects play an important role in prescribing Ticagrelor in the ACS & PTCA patients, reasons for its poor usage in common clinical practice was studied.
Authors and Affiliations
Venkata Sravani Polamraju
Keywords
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