A PROSPECTIVE AND RANDOMIZED DOUBLE BLIND STUDY TO COMPARE THE EFFECTIVENESS OF PROPHYLACTIC GRANISETRON VERSUS PETHIDINE FOR THE PREVENTION OF POSTOPERATIVE SHIVERING IN PATIENTS UNDERGOING ELECTIVE THYROID SURGERIES
Journal Title: GJRA-Global Journal For Research Analysis - Year 2019, Vol 8, Issue 3
Abstract
MATERIALS AND METHODS 90 Patients randomly allocated into three groups- qroup P, qroup G, qroup S in each group 30patientswere Selected Group P Patients were given Inj Pethidine 25 mg intravenously 5 minutes before induction of general anaesthesia. Group G Patients were given Inj Granisetron 40 microgram /Kgintravenously 5 minutes before induction of general anaesthesia. Group S Patients were given Saline intravenously 5 minutes before induction of general anaesthesia. RESULTS Postoperative shivering graded after extubation at 15 and 30 minutes interval no shivering in Pethidine group 83.3% {n= 25} Granisetron, qroup 73% {n=22} Placebo qroup 27% {n=8} P value not signicant between P & G group but signicant in Placebo qroup {P <0.05}. shivering occurs at grade 3in pethidine group 7% [n=2] Granisetron group 10%[n=3], Placebo group 60%[n=18] P value statistically not signicant between P & G groups but signicant in Placebo qroup {P <0.05}. CONCLUSION From this study prophylactic use of both Pethidine and Granisetron were equally effective for the prevention of postoperative shivering
Authors and Affiliations
DR. C. KALAIYARASI, Dr. A. Gopinath
Keywords
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