A prospective comparative study to compare cardiovascular response to laryngoscopy and intubation after induction of anaesthesia by propofol and etomidate
Journal Title: Indian Journal of Clinical Anaesthesia - Year 2017, Vol 4, Issue 1
Abstract
Context: Etomidate is having more stable cardiovascular response as compared to propofol during laryngoscopy and intubation. Aims: The present study compares the effect of propofol and etomidate on cardiovascular response to laryngoscopy and intubation. Settings and Design: This prospective comparative study was conducted at a tertiary care hospital in central India. Methods and Material: Hundred healthy patients of both sex aged between 18 to 45 years, ASA physical status I & II, scheduled for elective surgery under general anaesthesia were selected. Patients in group P (n=48) were induced with propofol 2.5 mg/kg i.v. and group E (n=47) were induced with etomidate 0.3 mg/kg i.v. Patients’ haemodynamic and cardiovascular parameters were recorded before induction (T1), before intubation (T2) and 1, 3, 5 and 10 minutes afterwards. The haemodynamic parameters before induction i.e. T1 was taken as baseline. Statistical analysis used: The data was collected using Microsoft Excel software and was analysed using SPSS software version17.0. Results: There was significant difference regarding systolic blood pressure, diastolic blood pressure and mean arterial pressure among two groups. Hypotension was seen in 18.8% patients in group P after induction while there was none in group E. Conclusions: Etomidate is having more stable cardiovascular response as compared to propofol during laryngoscopy and intubation.
Authors and Affiliations
Kaushal Kabir, Gaurav Acharya, Manish Banjare, KK Arora, Sachin Kumbhare
Keywords
Related Articles
- EP ID EP311272
- DOI 10.18231/2394-4994.2017.0010
- Views 95
- Downloads 0
Prognostic applicability of simplified acute physiology score (saps 3) in critically ill adult surgical patients in a tertiary Indian hospital: A preliminary study
Introduction and Aims: Prognostic indices are infrequently practiced in surgical intensive care units (SICU) of Indian tertiary care hospitals to assess the overall outcomes. Simplified Acute Physiology Score 3 (SAPS 3)...
Subacute sclerosing panencephalitis - A fatal complication of measles
Subacute Sclerosing panencephalitis (SSPE), also known as Dawson’s disease or measles encephalitis, is an extremely rare and fatal subacute infection caused by a persistent defective measles virus (MV). It mostly develop...
Assessment of efficacy of intravenous fentanyl citrate for attenuation of hemodynamic responses during laryngoscopy and endotracheal intubation
Introduction Laryngoscopy and intubation result in stimulation of larynx pharynx epipharynx and trachea which are extensively innervated by autonomic nervous system The parasympathetic supply is via the vagus and sympath...
Comparison of laryngoscopy and intubating conditions using kings vision laryngoscope and C-MAC video laryngoscope
Introduction and Aims Currently wide arrays of video laryngoscopes are available to facilitate laryngoscopy and endotracheal intubation in routine and difficult airway patients intensive care units ICU and emergency sett...
Broken epidural catheter: What next to do?
Introduction of epidural catheters has increased the benefits of epidural block by several folds permitting extension of neuraxial blockade for extended period of time Although its insertion is safe but removal may be as...