A Prospective Drug Utilization Study in Geriatric Hypertensive Patients in a Tertiary Care Hospital, Mumbai

Journal Title: Journal of Advances in Medicine and Medical Research - Year 2015, Vol 5, Issue 2

Abstract

Introduction: The geriatric population assumes great significance in terms of both preventive and curative health care services utilized. The patho-physio-psychological changes associated with ageing make their problems unique. In the geriatric population, hypertension accounts for a huge proportion of cardiovascular and all cause mortality and morbidity. We conducted a study to describe the patterns of antihypertensive drug use in the geriatric population, compare it to the current recommendations and conduct an analysis using the WHO-INRUD drug use indicators. Methods: A prospective cross sectional drug utilization study of 100 prescriptions of hypertensive patients (as per JNC 7) of either sex and ≥60 years was undertaken as per the WHO – DUS and the STROBE guidelines. Results: Statistically significant relation was found between BP control, and addictions and CIRS-G score. The 100 prescriptions contained 344 drugs, out of which, 171 were antihypertensive drugs. Three percent of antihypertensive drugs were prescribed by generic names. Seventy nine percent of antihypertensive drugs were prescribed from the ‘hospital drug schedule’. Amlodipine, Hydrochlorothiazide, Losartan and Telmisartan were prescribed to 79%, 24%, 11%, 11% respectively. The combination of ARB (Angiotensin Receptor Blocker) + Diuretic was prescribed to 36% and that of ARB + CCB (Calcium Channel Blocker) was prescribed to 21%. The PDD/DDD ratios of Carvedilol, Losartan, Furosemide and Telmisartan were 0.7, 0.8,1 and1.2, respectively. Conclusion: Creating awareness regarding the role of addiction in BP control and advocating lifestyle changes is paramount in HTN management. Overall, the principles of rational prescribing were followed. The prescription pattern observed was as per current recommendations.

Authors and Affiliations

Gauri Billa, Shirish Joshi, Santosh Salagre, Karan Thakkar

Keywords

Related Articles

Health Maintenance Organization-Federally Qualified Health Center (HMO-FQHC) Collaboration to Provide After-Hours Pediatric Primary Care: A Feasibility Study

Aims: Examine feasibility, implementation and impact of a Health Maintenance Organization (HMO)-Federally Qualified Health Center (FQHC) collaboration in providing after-hours care as an Emergency Department (ED) diversi...

Effect of Resistive and Aerobic Exercise on Reducing Insulin Sensitivity during Pregnancy

Aims: The purpose of this study was to evaluate whether a combined resistive and aerobic training program would improve insulin sensitivity compared with aerobic training alone in pregnant women. Place and Duration of S...

Missed Clavicular Fracture in an Adult without Head Injury or Polytrauma Review of Literature and a Rare Case

We present a case of missed clavicular fracture in a patient with an associated wrist fracture but without head injury. This is the first case of missed clavicular fracture in an adult, despite adequate imaging, and with...

Development and Validation of the Emergency Department Geriatric Readmission Assessment at Yale (ED GRAY): Part 2, Prognostic Accuracy

Objective: The Emergency Department (ED) Geriatric Readmission Assessment (ED-GRAY) is a 16-item questionnaire we developed that can be used to evaluate the prognostic ability to determine if geriatric patients will reci...

Knowledge and Factors Associated with Treatment Compliance among Diabetes Mellitus Patients in Selected Hospitals in Ibadan, Oyo State, Nigeria

Diabetes mellitus (DM) is an emerging public health problem of the 21st century that threatens to overwhelm the health care system and has been identified as the sixth leading cause of death worldwide. The overall preval...

Download PDF file
  • EP ID EP348041
  • DOI 10.9734/BJMMR/2015/12876
  • Views 54
  • Downloads 0

How To Cite

Gauri Billa, Shirish Joshi, Santosh Salagre, Karan Thakkar (2015). A Prospective Drug Utilization Study in Geriatric Hypertensive Patients in a Tertiary Care Hospital, Mumbai. Journal of Advances in Medicine and Medical Research, 5(2), 178-190. https://europub.co.uk/articles/-A-348041