A PROSPECTIVE OBSERVATIONAL STUDY ON ADVERSE CUTANEOUS DRUG REACTIONS IN A TERTIARY CARE CENTRE IN SOUTH INDIA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 20
Abstract
BACKGROUND An adverse drug reaction (ADR) is defined as any noxious, unintended and undesired effect of a drug, which occurs at doses used in humans for diagnosis, prophylaxis or therapy. 1 Cutaneous adverse drug reactions are one of the most common types of ADRs. The incidence of cutaneous adverse drug reactions varies from 1 – 3% in developed countries to 2 - 5% in developing countries.2 Aims and Objectives: To determine the prevalence of cutaneous adverse drug reactions in our hospital and to identify the clinical patterns of the drug eruptions and the common drugs implicated among our patients. MATERIALS AND METHODS The study was done over a period of two years. Hundred patients presenting with cutaneous drug reactions were registered and analysed. The demographic details were recorded, and a thorough clinical examination was done. RESULTS Out of the hundred patients enrolled, 45 were males and 48 were females. There were 2 male children and 5 female children. Most of the patients were in the age group of 21 - 30 and 31 - 40 years, 21 each. Antibiotics were the commonest (30 patients) group of drugs implicated followed by analgesics (29 patients). Fixed drug eruptions were the commonest reaction pattern noticed (32 patients) followed by urticaria and angioedema (25 patients). Females were more commonly affected than males. CONCLUSION The clinical pattern of the cutaneous adverse drug reactions is varied in this locality, the knowledge of which is essential for the clinicians.
Authors and Affiliations
Suganthy Valavan, Karpagam Baliah, Parimalam Kumar
Keywords
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- EP ID EP431403
- DOI 10.14260/jemds/2018/552
- Views 88
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