A prospective observational study to evaluate the pattern of pituitary dysfunction in patients with acute phase of subarachnoid haemorrhage.
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 11
Abstract
Introduction: SAH has been predicted as a risk for hypothalamic–pituitary dysfunction. Pattern of hormonal impairments has been shown to differ substantially. Cause of these functional problems remains, at least in part, unclear and many of these symptoms are similar to those occurring in patients with untreated hypopituitarism. Aim and objectives: The present study was performed to observe the pattern of pituitary dysfunction in patients with acute phase of subarachnoid haemorrhage, who were admitted in the intensive care unit of a tertiary care hospital. Materials and Methods: Anterior pituitary hormones were analysed in 98 patients within 72 h after spontaneous SAH. Out of 98 patients in our study, 29 (29.5%) patients had no hormonal dysfunction, 21 (22%) patients had single hormonal dysfunction, 26 (26%) patients had abnormality of two hormones and 21 (22%) patients had more than two hormonal dysfunction. found subclinical hypothyroid in 9 patients with mean TSH levels of 6.16±1.41 µIU/ml. In 4 patients TSH levels were >10 µIU/ml. 24 male patients were having low testosterone levels. Low estradiol was detected in 9 (30.8%) female patients. Conclusion: Our study confirmed that anterior pituitary hormonal deficiency occur in a substantial number of patients at initial stage of sub arachnoid haemorrhage, whether this occurs later on needs to be followed and studied. Thus it is important to evaluate these patients continuously with periodic endocrine examination and follow up.
Authors and Affiliations
Mehraj Ud Din
Keywords
Related Articles
- EP ID EP522509
- DOI -
- Views 85
- Downloads 0
Solitary Peutz-Jeghers Type Polyp- A Rare Presentation
solitary Peutz-Jeghers type is a hamartomatous polyp without associated mucocutaneous pigmentation or a family history of Peutz-Jeghers Syndrome. Peutz-Jeghers type hamartomatous polyps are associated with a lower risk...
Microbiological Profile of Ventilator Associated Pneumonia at Tertiary Care Hospital Attached To S. P. Medical College Bikaner
Introduction: Ventilator associated pneumonia (VAP) is an important form of hospital acquired pneumonia, specifically refers to pneumonia developing in mechanically ventilated patients for more than 48 hours after trache...
Markers of Ovarian Function: Anti-Mullerian Hormone (Amh) Vs. Others
Aim: the aim of this study is to determine day 3 serum AMH, FSH, LH, Estradiol (E2), Inhibin B levels, ovarian volume and antral follicle count to assess ovarian function. Methods: The study was conducted on 130 infertil...
Stress: Mechanisms and Its Oral Implications
Stress is the body’s response to any physical, mental or emotional demand placed on it. It is automatic process and also known as the “fight-or-flight-or-freeze” reaction, or the stress response. Stress is the way human...
Aetiology and Clinical Profile of Patients Aged >30 Years with Seizures.
Background: Seizures are the common neurological disorders found throughout the world and are routinely encountered in the clinical practice. The aim of this study was to evaluate the aetiology of seizures in patients ag...