A PROSPECTIVE RANDOMISED COMPARATIVE STUDY OF EVALUATION OF EFFECT OF PROPOFOL AND DEXMEDETOMIDINE TO REDUCE SEVOFLURANE INDUCED EMERGENCE AGITATION IN YOUNG CHILDREN UNDERGOING DAY CARE SURGERY
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 71
Abstract
BACKGROUND In children Sevoflurane is associated with delirium upon recovery from anaesthesia, cause is not clear. It is called emergence delirium or emergence agitation. This is usually seen in first thirty minutes and it is described as a disturbance in children awareness and attention to environment with disorientation and perceptual alterations including hypersensitivity to stimuli and hyperactive motor behaviour in the immediate post anaesthesia period. Propofol is effective in preventing emergence agitation (E.A). Dexmedetomidine is reported to reduce the frequently of EA. So we have conducted a study to evaluate, the efficacy of propofol in comparison with dexmedetomidine, to reduce the Emergence agitation with Sevoflurane anaesthesia in paediatric patients. MATERIALS AND METHODS Patient selected for this study were randomly divided in to two groups, group A, is a propofol group, group B is dexmedetomidine group. The severity of EA was evaluated by using paediatric anaesthesia emergence delirium scale (PAED) devised by Sikich and lerma. Incidence of emergence agitation and PAED score were noted every 5 min up to first 30 min. RESULTS Regarding Incidence of emergence agitation and PAED score, we have found that number of patient with emergence agitation was more in propofol group than dexmedetomidine group at T0, T5 ,T10, T15 and T20 but not at T30. Accordingly the PAED score was high in group A that is propofol group then group B at T0 ,T5 ,T10 and T15 but at T20 and T30 it was same in both the group. CONCLUSION We have found in our study that dexmedetomidine is more effective than propofol in reducing the severity and incidence of emergence agitation. There is no significant difference in the duration of stay in patient in PACU but time of emergence was also delayed in dexmedetomidine Group.
Authors and Affiliations
Ramkrishna S. Ch. S, Kalyan Chakravarty Y. , Rao A. S. K. , Anand Acharya
Keywords
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- EP ID EP277885
- DOI 10.18410/jebmh/2017/843
- Views 37
- Downloads 0
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