A prospective randomised study to compare serum lactate level in patients receiving induced controlled hypotension with propofol and isoflurane for functional endoscopic sinus surgery
Journal Title: Medpulse International Journal of Anesthesiology - Year 2017, Vol 8, Issue 1
Abstract
Lactate which the metabolic end product of anaerobic metabolism is being used as a marker of hypoperfusion. It is seen is various conditions which decrease tissue perfusion and hence used as a marker for inadequate cellular oxygen delivery during hypotensive anaesthesia in our study which compares the effect of propofol and isoflurane hypotensive anaesthesia during functional endscopic sinus surgery (FESS). In our study 60 patients of ASA I and II undergoing FESS where divided into two groups randomly to receive either isoflurane (group 1) or propofol (group 2) intraoperatively to maintain a mean areterial pressure between 60-70mmHg. The vitals, blood loss, the quality of the surgical field and serum lactate levels where measured and recorded at appropriate intervals and satistically analysed. There was a raise in serum lactate levels with induction of hypotensive anaesthesia but the raise was within physiological limits and returned to baseline within 60mts of recovery. There was no significant difference between the two group in terms of heart rate, mean arterial pressure, blood loss, operative field or serum lactate levels.
Authors and Affiliations
S Narmatha, K Radhika, R Uma
Keywords
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