A Prospective Study of Clinico–Histopathological Correlation among Leprosy Patients Attending a Tertiary Referral Centre in Assam, in This Post Elimination Era
Journal Title: International Journal of Health Sciences and Research - Year 2017, Vol 7, Issue 4
Abstract
Background: Leprosy, also known as Hansen’s disease, is a chronic, infectious and treatable disease that primarily affects the skin and the peripheral nerves. Clinico-histopathological correlation of leprosy case assumes a pivotal role in early diagnosis and proper labeling of a case and thus leads to better management of patients. Aim: To study the clinical and histopathological correlation among leprosy patients attending a tertiary referral centre in this post elimination era. Materials & Methods: Study was conducted at a tertiary hospital during July, 2014 to June, 2015. Total 72 new cases of leprosy were selected purely on clinical ground (WHO criteria) attending dermatology OPD. Then these patients were subjected to slit skin smear examination and skin biopsy. Histopathological classifications of sections were done on the basis of the scheme put forth by Ridley (1974) and later it was correlated with the clinical classification across the Ridley-Jopling spectrum to evaluate the concordance among two. Results: Both clinically and histopathologically, BT constituted the predominant group 52.80% and 41.66% respectively. The overall clinico-histopathological correlation was seen in 41 cases (56.94%). Maximal concordance was noted in indeterminate leprosy (100%), followed by polar forms of leprosy i.e. LL (80%) & TT (75%). The least concordance was seen in mid-borderline leprosy (16.66%). Conclusion: This study highlights the importance of histopathological examination in assessing the leprosy cases as the under-treatment of MB cases will lead to persisters in the community and thus spread of disease and possible danger of drug resistance too in this era of elimination.
Authors and Affiliations
Dr. Debeeka Hazarika
Study of Clinico-Cytological Profile of Female Patients from Rural Areas of Telangana Presenting to a Tertiary Care Centre with Gynecological Complaints
Introduction: Cancer cervix being the most common cancer of the female population in India needs early screening and interventions in high-risk females. Pap smears is the gold standard method of screening women of all ag...
Prevalence and Aetiology of Pathological Vaginal Discharge among Third- Trimester’ Women Attending Antenatal Care at Kampala International University Teaching Hospital
Background: A vaginal discharge means any secretion originating from the vagina except blood. Pathological vaginal discharge predisposes to preterm labor and prematurity which is a leading cause of infant mortality in th...
Life Satisfaction in Adolescents with the Effects of Perceived Stress in Students of Selected Schools of Dharan Municipality
Background & Objectives: To safeguard adolescent mental well-being, it is important to create social environments that offer protective factors for mental health and limit exposure to risk factors for mental disorders. O...
Mental Foramen Position, Shape and Size of Mental Foramen in Adult Human Mandibles
Purpose of this study was to investigate the most common accurate position of the mental foramen in selected persons which helps in several clinical procedure and nerve block anesthesia. The study sample included 50 huma...
Clinico-Etiological Study of Reproductive Tract Infections in Sexually Active Women in Rural Area
Context: Reproductive tract infections (RTIs) including sexually transmitted infections (STIs) are recognized as major public health problem globally. They are second important cause of healthy life lost among women of r...