A prospective study of comparison of clinical profile, complication and outcome of plasmodium vivax versus plasmodium falciparum in children
Journal Title: IP International Journal of Medical Paediatrics and Oncology - Year 2018, Vol 4, Issue 4
Abstract
Introduction Malaria is a life threatening disease but is curable and preventable As per data of WHO in 2017 there were an estimated 219 million cases of malaria in 90 countries As plasmodium Vivax malaria has been considered to have a benign course with less mortality most of the research is focussed on plasmodium falciparum But in recent years there are number of studies conducted in India and other countries has highlighted that plasmodium vivax can cause severe and fatal malaria in paediatric patients Based on this background we have designed a prospective study to evaluate clinical profile complication and outcome of plasmodium vivax and compare it with plasmodium falciparum malariaMaterials and Methods Present study is a prospective study conducted in the department of paediatrics Konaseema institute of medical science Amalapuram Andhra Pradesh during the period from Jan 2015 to October 2018Data regarding patient age sex clinical presentation investigation complication and outcome are recorded Lab investigation like haemoglobin total leukocyte cannot platelet count bleeding time clotting time blood sugar blood urea serum creatinine serum Bilirubin SGOT and SUPT were some for all these investigation standard laboratory procedure was followedResult In present study 60 patient admitted with proven malaria to our hospital were analysed Severemalaria was present in 41112 p vivax infection patients and in 2841 P falciparum infection patient4 patients having bleeding manifestation in vivax group and 2 patient having bleeding manifestation in P falciparum group Jaundice was present in 4 p vivax infection patients and 2 P falciparum infection patients 12 3333 P vivax patients were presented with shock 83333 patient in falciparum group presented with shock Renal failure was present in 41112 p value patient and 2 84 patients with P falciparum infection Cerebral malaria was present in 3833 p vivax infection patient and 284 p falciparum patients 2556 patient in Pvivax infection and 1111 patient in p falciparum developed ARDSpulmonary edemaDiscussion and Conclusion From present study we would like to conclude that both type of infection were presented with complication organomegaly was common in Vivax infection but thrombocytopenia was common in falciparum infection Hepatic and renal complications were more common in Vivax patients cerebral malaria was present in both groupsKeywords Plasmodium vivax Plasmodium falciparum Children Complication and outcome
Authors and Affiliations
P Suresh Babu, K Visweswara Rao, Anand Acharya
Keywords
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- EP ID EP482948
- DOI 10.18231/2581-4702.2018.0033
- Views 103
- Downloads 0
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