A prospective study of comparison of control of bleeding with tranexamic acid vs placebo in acute trauma patients

Journal Title: Medpulse International Journal of Anesthesiology - Year 2018, Vol 6, Issue 1

Abstract

In our trauma care centre we receive around 2000 cases per month ranging from Polytrauma, Faciomaxillary injury, Both bone fracture Upper limb, Lower limb, Vascular trauma, Abdominal injuries of patients of variable age groups. Methods: 30 patients of each group were chosen with the various trauma mentioned above. We started the Randomised Prospective Comparative Clinical study with Tranexamic acid 1 gram Intra Venously in 100 ml of Normal saline within 30 minutes of the arrival at trauma ward. The other group had 100 ml of Normal Saline. The case chosen were between 20 to 60 years of age both male and female. Inj. Tranexamic acid group Vs control group were chosen with similar condition like Right facial trauma Vs Left facial trauma. Conclusion: We conclude that infusion of Tranexamic acid reduces intraoperative blood loss (P = 0.003).

Authors and Affiliations

Rajashree G R, Anuradha Swaminathan

Keywords

Related Articles

Comparison of Analgesic Efficacy of Butorphanol and Fentanyl in Various Surgeries

Background: An ideal perioperative analgesic should offer protection against the pressor response should provide intense analgesia sufficient to relieve pain of surgical incision, maintain the haemodynamic parameters and...

Comparative study of effects of tramadol and midazolam added to bupivacaine (0.25%) in supraclavicular brachial plexus block for upper limb surgeries

Background: Supraclavicular brachial plexus block is commonly used for upper limb surgeries due to its effectiveness, performance and margin of safety. To minimize the drawbacks of bupivacaine, adjuvants are usedto impro...

Comparison of post-operative analgesic efficacy of dexmedetomidine infusion versus infiltration at surgical wound site in microdiscectomies

Background- Patient undergoing spine surgery often suffer from moderate to severe postperative pain and may require large doses of analgesic drugs. Optimizing postoperative pain improves clinical outcomes and increases s...

A randomized, prospective, comparative study to evaluate the sensory blockade properties of 3ml of 0.5% isobaric levobupivacaine and 3ml of 0.5% isobaric ropivacaine for spinal anaesthesia in patients undergoing elective lower limb orthopaedic surgeries

Background: Regional anaesthesia is the preferred technique for most of the lower abdomen and lower limb surgeries. Bupivacaine has increased incidence of fatal cardiac toxicity after accidental intravascular injection,...

A study of general anesthesia versus cervical block for the surgery of thyroid at tertiary health care center

Background: Historically, Thyroid and parathyroid surgery was done initially under local anesthesia. Aims and Objectives: To study General anesthesia versus cervical block for the surgery of thyroid at tertiary health ca...

Download PDF file
  • EP ID EP451533
  • DOI 10.26611/1015612
  • Views 151
  • Downloads 0

How To Cite

Rajashree G R, Anuradha Swaminathan (2018). A prospective study of comparison of control of bleeding with tranexamic acid vs placebo in acute trauma patients. Medpulse International Journal of Anesthesiology, 6(1), 6-11. https://europub.co.uk/articles/-A-451533