A Prospective Study of the Efficacy of Clonidine added to Bupivacaine as Compared with Bupivacaine alone used in Supraclavicular Brachial Plexus Block for Upper Limb Surgeries
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 11
Abstract
Introduction: Relief of pain during and after the surgery forms the pivot in conduction of anaesthesia. The aim of our study was to compare the effect of a randomized controlled double-blind prospective study of the efficacy of clonidine added to bupivacaine as compared with bupivacaine alone used in supraclavicular brachial plexus block for upper limb surgeries. Material and Methods: The present study was conducted at Gandhi Hospital, Secunderabad. The study protocol was placed for review and approval of the institutional ethical committee. A written informed consent was obtained from every subject before initiation of any related procedure. Fifty patients of either sex in age group of 18 – 70 years and ASA status I and II scheduled for upper limb surgery under supraclavicular brachial plexus block were randomized to either. Study Group(S) received 40 ml of 0.25% Bupivacaine + 150 mcg of clonidine, Control Group(C) received 40 ml of 0.25% Bupivacaine + Nacl of 0.9% solutions. Results: The present study was carried out in 50 patients of ASA grade I/II in two groups for the upper limp surgeries under supravcalvicular brachial plexus block. Twenty five patients were given clonidine as an adjuvant to bupivacaine and twenty five were given bupivacaine alone. The hemodynamic and the analgesic characteristics were recorded and statistically analysed. The following conclusions were drawn from our present study. The time of onset of sensory and motor blockades were fast in clonidine group. The duration of sensory and motor blockades were prolonged with usage of clonidine. Conclusion: From the above study it is concluded that clonidine is a better adjuvant to bupicaine for supraclavicular brachial plexus block, it provides faster, longer duration of analgesia and sedation with hemodynamic stability.
Authors and Affiliations
Nama Nagarjuna Chakravarthy, K. Radha Ramana Murthy
Keywords
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