A Qualitative and Quantitative Proteomic Study of Human Microdialysate and the Cutaneous Response to Injury
Journal Title: The AAPS Journal - Year 2011, Vol 13, Issue 2
Abstract
The online version of this article (doi:10.1208/s12248-011-9269-6) contains supplementary material, which is available to authorized users.
Authors and Affiliations
Carolyn Gill, Erika Parkinson, Martin K. Church, Paul Skipp, Daniel Scott, Andrew J. White, C. David O’Connor, Geraldine F. Clough
Evaluating In Vivo-In Vitro Correlation Using a Bayesian Approach
A Bayesian approach with frequentist validity has been developed to support inferences derived from a “Level A” in vivo-in vitro correlation (IVIVC). Irrespective of whether the in vivo data reflect in vi...
Target-Mediated Disposition Model Describing the Dynamics of IL12 and IFNγ after Administration of a Mifepristone-Inducible Adenoviral Vector for IL-12 Expression in Mice
The online version of this article (doi:10.1208/s12248-012-9423-9) contains supplementary material, which is available to authorized users.
Design and Evaluation of a PEGylated Lipopeptide Equipped with Drug-Interactive Motifs as an Improved Drug Carrier
The online version of this article (doi:10.1208/s12248-013-9536-9) contains supplementary material, which is available to authorized users.
Effective Absorption Modeling in Relative Bioavailability Study Risk Assessment
Absorption modeling is an excellent strategic fit to perform a risk assessment for relative bioavailability (RBA) studies as it provides direct input into the question that is at the core of the RBA decision, namely, how...
Quantification of Swelling and Erosion in the Controlled Release of a Poorly Water-Soluble Drug Using Synchrotron X-ray Computed Microtomography
The hydration layer plays a key role in the controlled drug release of gel-forming matrix tablets. For poorly water-soluble drugs, matrix erosion is considered as the rate limiting step for drug release. However, few inv...