A randomised control study: To evaluate the effect of oxytocin plus misoprostol versus oxytocin or misoprostol alone in reducing blood loss at cesarean section
Journal Title: International Journal of Clinical Obstetrics and Gynaecology - Year 2018, Vol 2, Issue 2
Abstract
Purpose: To compare the effect of oxytocin plus misoprostol versus oxytocin or misoprostol alone in reducing blood loss at ceasarean section. Methods: This randomized control study included 126 primigravida patients undergoing lower segment cesarean section under spinal anesthesia and fulfilling selection criteria. Patients were randomly allocated to one of the three groups to receive 20 IU infusion of oxytocin (Group-O), 400 µg sublingual Misoprostol tablet (Group-M) or 200µg Misoprostol tablet plus 10 IU infusion of oxytocin (Group-M+O) after delivery. The main outcome measures-Blood loss, Heamoglobin values measured both before and 24 hr following surgery, adverse effects were recorded. Results: There Mean blood loss during surgery was significantly less in combined lower doses of oxytocin plus misoprostol in compared to using higher doses of oxytocin and misoprostol alone (p<0.001). Mean haemoglobin changes significantly less in M+O group in compared to other group(P<0.001). Conclusion: The combined use of lower dose of oxytocin plus misoprostol significantly decrease the amount of blood loss during and after cesarean section and minimal side effects compared to higher dose of oxytocin and misoprostol alone.
Authors and Affiliations
Dr. Anita, Manju Sharma, Lata Rajoria, Seema Mehta
Keywords
Related Articles
- EP ID EP502255
- DOI -
- Views 125
- Downloads 0
High serum lactate dehydrogenase levels as a prognostic marker for morbid perinatal outcome in pre eclampsia
Introduction: Hypertension during pregnancy is an important causative factor of perinatal and maternal morbidity and mortality globally. There are several biochemical markers like ALP, AST, ALT, LDH, Uric acid to ascerta...
Prevalence and pattern of congenital anomalies at tertiary health care hospital
Background: Congenital abnormality is an abnormality of structure, function or body metabolism that is present at birth and results in physical or mental disability or is fatal. Congenital anomalies are the important cau...
Efficacy of ormeloxifene in the management of DUB
Aims and objectives: To establish the role of ormeloxifene in the medical management of DUB. Materials and Methods: Hundred women with DUB enrolled in the study group and 60mg of ormeloxifene was given orally for three m...
Critical evaluation of umbilical cord morphometry in pregnancies with normal and abnormal glucose metabolism: An ultrasound based study
Background: In gestational diabetes both the foetus and placenta experiences a diversity of structural and functional changes. While the changes in the placenta such as placental size, oedema, associated placental abnorm...
Postmenopausal bleeding and its evaluation: Prospective study in a tertiary care center
Objective: To study the prevalence of postmenopausal women in the urban population, its clinical presentation, histopathology incidence of malignancy. Method and material: A prospective study performed in ESIC medical co...