A Randomised Prospective Double Blinded Study of Intrathecal Levobupivacaine with Fentanyl Verses Clonidine for Infraumblical Surgeries
Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2019, Vol 6, Issue 1
Abstract
Background and aims: Subarachnoid block can be performed with many local anaesthetic agents. Besides hyperbaric bupivacaine even isobaric levobupivacaine and ropivacaine can also be used with minimal cardiotoxicity. Adjuvants like opiods and alpha-2 agonist prolongs the duration of levobupivacaine action. The aim of the present study is to compare fentanyl and clonidine effect used as adjuvants to levobupivacaine with respect to onset of sensory and motor blockade; maximum level attained and the required for the same; duration of blockade and post operative analgesia. Materials and Methods: After ethical committee approval, 80 patients posted for infraumblical surgeries divided into two groups. Group LF received 15 mg of levobpivacaine with 25µg fentanyl whereas group LC received 15 mg of levobupivacaine with 30µg clonidine. The volume of solution was 3.5 ml in both groups. Hemodynamic, sensory and motor characteristics were monitored. Results: Onset of sensory and motor blockade as well as regression of both was faster with fentanyl than clonidine. There was slight fall in heart rate and mean arterial pressure in both the groups after intrathecal drugs but it was more with clonidine. Bradycardia and hypotension was noted more with clonidine than fentanyl which was easily manageable. Though the onset was delayed, sensory, motor and analgesic effect was prolonged with clonidine. Conclusion: Levobpiacaine can be safely used for spinal anaesthesia in infraumblical surgeries. Adding fentanyl causes early onset of action whereas clonidine has more prolonged action.
Authors and Affiliations
Greeshma N Murdeshwar
Keywords
Related Articles
- EP ID EP601093
- DOI 10.21088/ijaa.2349.8471.6119.34
- Views 77
- Downloads 0
Anticipated Challenges during Anaesthetic Management of a Patient with Kartagener Syndrome: Case Report
The trait is Autosomal recessive. Primary ciliary dyskinesia is the major patho-physiology with Sinusitis, Bronchiectasis and Situs Invertsus as the characteristic features. Preoperatively Respiratory and Cardiovascular...
Comparitive Study of I-Gel Vs Supreme LMA in Anaesthetised Patients on Spontaneous Ventilation
The aim of this study is to study and compare two supraglottic airway devices I-gel and supreme laryngeal mask airway, in anaesthetised adult patients with spontaneous ventilation, with respect to Ease of insertion, Numb...
Narrative Palliative Care: A Method for Building Empathy
Palliative care can be provided in acute care settings, hospice, patient’s own home, ambulatory clinics etc and aims to provide dignity, respect and humble care to the sick with objective of managing pain, understanding...
Tamsulosin Reduces Incidence of Post Operative Urinary Retention Post Spinal Anaesthesia: A Pilot Study
Introduction: One of the most common postoperative complaints after spinal anaesthesia is postoperative urinary retention (POUR). The prophylactic effect of tamsulosin in reducing POUR in post spinal anaesthesia has no...
An Observational Study to Compare Recovery of Elderly Patients from General Anaesthesia with Sevoflurane or Desflurane
Background: The clinical study was undertaken to compare the recovery of elderly patients from general anaesthesia with sevoflurane or desflurane with reference to spontaneous eye opening, obeying verbal commands, recall...