A Rare Case of Diosmin and Hesperidin Induced Chest Tightness and Dyspnea
Journal Title: The International Journal of Therapeutics - Year 2018, Vol 1, Issue 1
Abstract
Diosmin and hesperidin are medicines derived from flavonoids present naturally in the citrus fruits. It is given as a combination drug therapy for internal hemorrhoids. These drugs are considered safe when it is used up to 3 months. Serious reactions including respiratory adverse drug reactions (ADRs) are very rare with the use of these drugs. There are no case reports of presentation of diosmin and hesperidin induced chest tightness and dyspnea. A 65-years-old female patient admitted to hospital presented with diosmin and hesperidin induced chest tightness and dyspnea. Evaluating the presented ADRs confirmed to diosmin & hesperidin use and were stopped after clinical pharmacy opinion. No rechallenge was done considering the seriousness of ADRs. This case report will help in establishing a safety message among the patients and clinicians as they must be made aware of possible respiratory ADRs caused by these drugs.
Authors and Affiliations
Dr. Ambed Mishra, K Shamshavali, Shilpa Palaksha, Himanshu Patel, M Umesh, Dr. Nandini Singh Tanwar
Keywords
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- EP ID EP436182
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