A rare case of non-tuberculous mastitis
Journal Title: Journal of Medical and Scientific Research - Year 2016, Vol 4, Issue 3
Abstract
A 15-year-old girl presented with left breast lump with purulent discharge. During the last three months she lost 4 kg weight. There was evening rise of temperature which was not associated with joint pains or chills. She had received three courses of antibiotics earlier in the other healthcare center, with no response. Ultrasound scan showed multiple cutaneous sinuses and FNA report findings were suggestive of chronic granulomatous mastitis. As the patient was not responding to multiple antibiotics courses, HRZE (Anti Tubercular Treatment, ATT) was started. But after three months of ATT she developed multiple sinus tracts filled with fluid and with superficial ulcerations, which was aspirated, sent for analysis and oral Moxifloxacin 400 mg was added. DNA based line probe assay detected Non Tuberculous mycobacterium (NTM) and was referred for NTM species identification. Molecular genetics assay identified Mycobacterium chelonae/ Mycobacterium immunogenum species and HRZE regimen was stopped. Patient was started on oral clarithromycin, linezolid according to sensitivity report. She responded well and repeat ultrasound scan showed significant resolution of the sinus and there was no discharge. NTM should be considered for breast infections that recur despite standard antibiotic therapy or ATT.
Authors and Affiliations
Sarma L, Qureshi A, Chilana KAM, Putti N
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