A Rare Disease, Alkaptonuria Cause for Low Backache
Journal Title: Scholars Journal of Medical Case Reports - Year 2016, Vol 4, Issue 9
Abstract
Abstract:A rare case of Alkaptonuria (AKU) with Low backache (LBA) is being reported. AKU is a rare metabolic disorder inherited as an autosomal recessive mode that can cause premature degenerative arthritis of the spine and peripheral large joints. Homogentisic Acid (HGA) is an immediate degradation product in the metabolism of tyrosine and phenylalanine. It is characterized by darkening of the urine on standing and ascorbic acid pays an important role in the metabolism of tyrosine and phenylalanine. Incidence of this disease is 1:2,50,000 people. Hereby present a case of middle-aged man who developed low back pain secondary to AKU. Keywords:Alkaptonuria, low backache, homogentisic acid, ascorbic acid.
Authors and Affiliations
Dr Nagaraju B, Dr Anil Kumar KV, Dr Maryam Ghanadi Farnoud, Shekar HS, Dr Ranganath HD, Dr Ravindran M, Dr Ravi CM, Dr Yogesh . , Dr Ramachandra Setty S
Keywords
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