A Rare Seen Hemorrhage Disorder: Factor XI Deficiency Hemophilia C
Journal Title: Meandros Medical and Dental Journal - Year 2018, Vol 19, Issue 1
Abstract
Factor XI deficiency is a hemorrhage disorder which can be either autosomal recessive or/and autosomal codominant and effects both women and men. Factor XI deficiency is uncommon in non-Jewish general population and average frequency of disorder is 1/1 million. Clinical phenotype is nonhomogeneous and bleeding risk depends on individual’s reaction against hemostatic variances. There is a poor relation between the Factor XI plasma level and bleeding tendency. In case of Factor XI deficiency, uncommon, unlike hemophilia A and B, spontaneous hemorrhage, surgical or trauma sequent are at risk. Hemarthrosis and intramuscular bleeding are common in hemophilia A and B but not typically seen in Factor XI deficiency disorders. Common symptoms are easy bruising and nosebleed. History of the disorder mostly indicates the findings about the difficulty in staunching. In this case, after detecting the activated partial thromboplastin time length before the operation due to build upon mandibula, management of patients, having Factor XI deficiency hemophilia C which is a cause of rare seen hemorrhage disorder, are presented in terms of bleeding diathesis.
Authors and Affiliations
Samet Özer, Nafia Özlem Kazancı, Ergün Sönmezgöz, Şeyma Ünüvar, Nihat Akbulut
Keywords
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- EP ID EP283442
- DOI 10.4274/meandros.2043
- Views 108
- Downloads 0
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