A retrospective, non-randomized, clinical review on the effect of single-dose biosimilar Razumab injection in diabetic macular edema
Journal Title: International Journal of Experimental Research and Review - Year 2023, Vol 32, Issue 3
Abstract
Diabetic macular edema (DME) is one of the microvascular complications of diabetes and also coexists with diabetic retinopathy. The present study aims to investigate the effectiveness of single-dose biosimilar Razumab injection in diabetic macular edema. In this retrospective, non-randomized, clinical review on patients (n=50), 50 eyes with diabetic macular edema were selected and treated with a single dose of 2.3mg/0.23mL Razumab injection intravitreally. Visual acuity (VA) and macular thickness (MT), were evaluated for a period of up to 45 days after injecting biosimilar Razumab and were used to assess the effectiveness after treatment for 45 days. The results of the study showed that there was a significant increase in visual acuity and a marked reduction in macular thickness and the intraocular pressure (IOP) and anterior segment (AS) examination reverted to normal after the injection (Day 45). This study concludes that a single dose of biosimilar Razumab injection was effective in improving visual acuity and reducing macular thickness with no ocular concerns in diabetic macular edema patients.
Authors and Affiliations
Arul Balasubramanian, Jeyaprakash Balasubramanian, Atchaya Pugazhenthi, Chandru Balasivaraman, Divya Murugadass, Kothai Ramalingam
Keywords
Related Articles
- EP ID EP720648
- DOI 10.52756/ijerr.2023.v32.010
- Views 49
- Downloads 0
Apoptosis and Autophagy: Therapeutic Implications in Cancer
Despite the advances in the medical field so far, cancer remains a global health priority even now. Considering the drug resistance and the failure of cancer therapies to achieve complete eradication of cancer cells in c...
A report groundwater arsenic contamination assay in the delta area of West Bengal
Groundwater contaminated with arsenic adds an extra percentage of arsenic load at the time of the different irrigated processes. In an arsenic-contaminated locality, an experimental drinking water contamination study was...
The Voltage stability analysis for grid-connected PV system using optimized control tested by IEEE 14 &30 bus system
In the research work presented in this paper, we present a grid-connected solar photovoltaic (PV) system, which is focused on various factors, such as the low oxide emission and high energy efficiency of the system. Sola...
Nitrogen fixing Cyanobacterial flora of Nadia District in West Bengal, India
Cyanobacteria play an important role in maintenance and build-up of soil fertility, consequently increase rice growth and yield as a natural bio fertilizer. The paddy field ecosystem provides a favourable environment for...
Assessment of undernutrition among Santal children of Bolpur-Sriniketan block of Birbhum District, West Bengal, India
Present cross sectional study was undertaken to assess the nutritional status of 348 pre-primary and primary school going Santal children aged 4 to 10 years which includes 186 boys and 162 girls of Bolpur-Sriniketan Bloc...