A Retrospective Observational Study of Dengue Fever in a Tertiary Care Center in Kerala
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 1
Abstract
Abstract Introduction: Dengue fever (DF) has emerged as an important infectious disease in Kerala with increasing incidence year after year. Knowledge of the clinical and laboratory profile is essential in the early diagnosis and appropriate management of this occasionally fatal illness. Materials and Methods: This is a descriptive, observational, record-based study done in the Department of Pediatrics, Government Medical College, Ernakulam. All children <15 years of age diagnosed to have DF were classified according to WHO new case classification guidelines, and their clinical and laboratory profile were recorded in a pro forma and analyzed. Results: Among the 78 dengue serology positive cases, 19.23% had DF with no warning signs, 57.20% had DF with warning signs, and 23.07% had severe dengue. The most common age group affected was 11-15 years (46%) with a male to female ratio of 1.68:1. Fever was seen in all cases followed by vomiting, myalgia, and headache. Hepatomegaly was a major clinical finding observed in 56.41%, while hypotension and low pulse pressure was seen in 12.82% of cases. Lab parameters showed leukopenia in 48.72% and severe thrombocytopenia 8.97% patients. Among those with elevated liver enzymes, aspartate aminotransferase rise was more than alanine aminotransferase in all cases, but none had values above 1000 U/L. Blood products were needed in 15.38% cases. There was no mortality observed in our study. Conclusion: DF continues to be a major health hazard in children. Strong clinical suspicion, early diagnosis with rapid tests and strict adherence to revised WHO guidelines definitely favors a very good outcome.
Authors and Affiliations
Peter Pathrose Vazhayil
Keywords
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