A retrospective study of head and neck re-irradiation for patients with recurrent or second primary head and neck cancer: Our hospital experience
Journal Title: Medpulse International Journal of Radiology - Year 2018, Vol 6, Issue 3
Abstract
Background: We report our experience with patients who received re-irradiation to the head and neck area for locoregional recurrences (LRR) or second primaries (SP) in a previously irradiated field. Methods: We reviewed 27 consecutive patients with a diagnosis of LRR or SP head and neck carcinoma treated with a second course of radiotherapy between June 2013 and July 2016. The main outcome measures were local control, and complications. Results: The median follow-up time was 24.7 months. There were 23 males and four females with a median age of 58 years (range: 40–70) years. The actuarial local control rate was 80% and 52 % at 1and 2 years, respectively. Three patients developed systemic metastases. The rate of grade 3 toxicity was 26 %, and that of grade 4 toxicity was 3 %. Conclusions: Continuous course re-irradiation in patients with LRR or SP head and neck cancer is feasible with acceptable toxicity. With current encouraging rates of local control and, this option should be discussed with patients who have few alternative therapeutic options.
Authors and Affiliations
Punita Pant, Jitendra Patel, B K Shewalkar
Keywords
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- EP ID EP533564
- DOI 10.26611/10136311
- Views 103
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