A retrospective study of quality management system at national reference laboratory in Mumbai - Highlighting quality in HIV testing
Journal Title: International Journal of Medical Science and Public Health - Year 2018, Vol 7, Issue 10
Abstract
Background: National reference laboratory (NRL) is a NABL certified center of HIV testing at National Institute of Immunohaematology. It has 2 union territories and 8 medical colleges as state reference laboratories (SRL’s) with integrated counseling and testing centers (ICTC’s) and blood banks (BB). It performs activities such as external quality assurance scheme, retesting of samples, and training programs. Objective: A retrospective study was carried out from 2012 to 2016 highlighting NRL’s unceasing efforts in maintaining stringency in the quality management system. Materials and Methods: Verification and calibration of pipettes, evaluation of hands-on expertise of technicians for Combaids assay and ELISA testing were assessed. Retesting of samples as part of the quality check was performed. Panel proficiency testing of all the centers was done twice annually. Results: In 2013 and 2016 (81% and 36% pipettes) passed calibration, respectively. Evaluation of Combaids assay was done on the scale of excellent, medium, and poor. In ELISA testing, 53% followed standard operating procedure, 42% followed good laboratory practice, and 5% showed reproducibility in results. Evaluation of BB technicians was done using the borderline reactive sample in January 13, September 13, and January 14 showed correct results by 5%, 0%, and 11%, respectively, while 78% ICTC technicians gave correct results in Combaids assay. Proficiency testing showed few discordant results every year with need for calibration and technical assessment of personnel while total retesting samples tested from year 2012 to 2016 were 419. Conclusion: NRL emphasizes on the preparation of borderline sample as in-house quality control sample, calibration of equipments, training regarding same for assuring reliability of test results.
Authors and Affiliations
Swati Yardi, Mehul Rajpurkar, Aruna Shankarkumar
Keywords
Related Articles
- EP ID EP488080
- DOI 10.5455/ijmsph.2018.1234318062018
- Views 105
- Downloads 0
Profile of autopsy cases at New Civil Hospital, Surat: a retrospective study
Background: The profiling of medicolegal cases is necessary in order to prevent the preventable casualties in future and to study the genuine crime rate in the area. Nowadays, road traffic accidents cause most of the...
Impact of educational intervention regarding anaemia and its preventive measures among adolescent girls of Government Commerce College of Gandhinagar city, Gujarat, India
Background: Adolescent girls are at a high risk for anaemia and malnutrition. Objective: To assess knowledge of adolescent girls regarding anaemia and its preventive measures before and after educational interventional t...
Histomorphological analysis of nonneoplastic skin lesions
Background: Nonneoplastic skin lesions include various skin conditions that have different histomorphological features. Many of nonneoplastic skin lesions are diagnosed by dermatologist but some others need biopsy...
Screening for depression in diabetic Patients
Background: Diabetes mortality is increased when accompanied with depression. Screening for depression is recommended by national and international authorities. Aims & Objective: To have an estimate of th...
Assessment of menopausal problems among rural women using modified menopause rating scale
Background: Menopause, although not a disease in itself, is associated with many frustrating physiological changes, diverse symptoms and psychological dysfunctions such as anxiety, depression, lack of concentration and d...