A Review of Solasodine Rhamnosides Therapy for In-Situ Squamous Cell Carcinoma on the Penis
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2014, Vol 4, Issue 2
Abstract
The majority of penile cancers develop from squamous cells within the skin resulting in a non-melanoma form of skin cancer, squamous cell carcinoma. Squamous cell carcinomas can develop anywhere on the penis, most appear on the foreskin in men who have not been circumcised or on the glans. Various types of squamous cell carcinomas ranging from Bowen’s disease, erythroplasia of Queyrat and Buschke-Lowenstein tumour have been identified on the penis. When detected early, these types of cancer can be successfully treated. However, the current treatment procedures have the potential for disfigurement and dysfunction of male genitalia, with associated psychological distress. A relatively new class of antineoplastic agents, consisting of the solasodine rhamnosides, solamargine and solasonine, are very effective and safe for the treatment of a variety of skin cancers and show promise for the treatment of internal cancers. Here, three cases of distinct squamous cell carcinomas on the penis, Bowen’s disease, erythroplasia of Queyrat and Buschke-Lowenstein tumour are reviewed which were successfully treated with a standard mixture of solasodine rhamnosides.
Authors and Affiliations
Bill E. Cham
An Innovative Crossword Puzzle Tool to Evaluate the Undergraduate Medical Student’s Knowledge in Forensic Medicine
Aims: The main aim is to expose the medical student after completion of their forensic medicine posting to the crossword puzzle and to study their responses given in feedback questionnaire with an effort to introduce an...
Prevalence and Trend of Geriatric Otorhinolaryngologic Diseases at University College Hospital, Ibadan, Nigeria
Aims: To determine the prevalence of otorhinolaryngologic diseases and the trend in the elderly people at the University College Hospital, Ibadan, Nigeria. Study Design: Retrospective study. Place and Duration of Study...
Correlation between Dental Caries and Salivary Albumin in Adult Indian Population– An In Vivo Study
Aim: To analyze the relationship between dental caries, albumin in young adults between the age group of 20 to 30 years from South Canara district, Karnataka with varying caries experience as determined by their caries p...
A New Fixed Dose Combination of Ceftriaxone + Sulbactam + Disodium Edetate for Definitive Treatment of Infections Due to Piperacillin/ Tazobactam Resistant Bacteria: A Retrospective Efficacy and Pharmacoeconomic Study
Objective: Present retrospective study was aimed to analyze comparative efficacy of fixed dose combination (FDC) (ceftriaxone + sulbactam + disodium edetate) and meropenem used alone or in combinations with other antibio...
A Case of Age Related Macular Degeneration Responding to a Statin – Perspective for a New Treatment
The newly started use of atorvastatin eliminated the need for further intravitreal injections of ranibizumab for 37 months in a case of wet form of age related macular degeneration(AMD). Repeated optical coherence tomogr...