A REVIEW ON BECKWITH WIEDEMANN SYNDROME
Journal Title: World Journal of Pharmaceutical Research - Year 2018, Vol 7, Issue 4
Abstract
Beckwith-Wiedemann syndrome (BWS) is a disorder involving overgrowth conditions. It is also characterized by a broad spectrum of symptoms and physical conditions that changes in range and severity from person to person. In this syndrome many individuals show conditions including above-average birth weight and increased growth after birth, uncontrolled growth of one side of the body. The syndrome occurs mainly in infants. Imprinted genes tend to be grouped together or clustered together. Several im In addition to H19 itself, this locus also produces a micro-RNA, called miR-675, an antisense protein coding transcript, called H19 opposite tumor suppressor (HOTS), and a long inter-genic antisense transcript called 91H printed genes are found in a cluster on chromosome 11p. The broad range of potential symptoms can affect many different organs of the body. Affected individuals may not have all of the symptoms listed in article. Cytogenetically detectable abnormalities involving chromosome 11p15 are found in 1% or fewer of affected individuals. Molecular genetic testing can identify epigenetic and genomic alterations of chromosome 11p15 in individuals with BWS. Surgery may be performed during early puberty to equalize significant differences in leg length secondary to hemi-hyperplasia; craniofacial surgery may benefit individuals with facial hemi-hyperplasia (a symptom of BWS). More symptoms are mainly Macrosomia, Macroglossia, Hemihyperplasia, Omphalocele, Placental mesenchymal dysplasia, Cleft palate and others.
Authors and Affiliations
Prajapati Anil
Keywords
Related Articles
- EP ID EP620539
- DOI -
- Views 124
- Downloads 0
CLINICAL IMPORTANCE OF VYADHI SANKARA- A REVIEW
The main aim and objective of Ayurveda is to maintain the health of Swastha Purusha and to eradicate the diseases of Atura Purusha. For this purpose, the diagnosis of diseases is very important and for this purpose Nidan...
EFFECT OF GRAPE SEED EXTRACT, GERVITAL, AGAINST METHOTREXATE INDUCED HISTOLOGICAL AND ULTRASTRUCTURAL ALTERATIONS IN TESTES OF ALBINO RATS
The present study was designed to investigate the effect of Gervital on testicular damage induced by the anticancer drug, methotrexate (MXT), in adult male albino rats. Forty male albino rats (Rattus norvegicus) were div...
A REVIEW ARTICLE ON CHIKUNGUNYA VIRUS
The recent emergence of Chikungunya has taken the concern of the health authorities of Bangladesh. There was a good number of record of Chikungunya patients in different hospitals as well as clinic. Although the fatality...
OPIATES DERIVATIVES MISUSE AMONG SAMPLE OF ATTENDANTS IN IBN RUSHED HOSPITAL IN BAGHDAD CITY.
Background: The substance abuse has become one of the major public health problems of present society. Recently there has been a rising in the incidence of substance abuse including that of opiates throughout the world....
POTENTIAL TEST AND COMPARATIVE TEST OF AMOXYCILLIN ANTIBIOTICS USED IN THE TREATMENT OF CASES OF RESISTANCE IN TASIKMALAYA, INDONESIA
Objective: ARI is an acute infection of any part of the respiratory tract including the paranasal sinuses, middle ear and pleural cavity caused by viruses, bacteria, rickettes. Amoxycillin is one of antibiotics to overco...