A REVIEW ON EBOLA VIRUS: SPECIFYING EPIDEMIOLOGY, PATHOGENESIS AND ITS TREATMENT APPROACHS
Journal Title: World Journal of Pharmaceutical Research - Year 2017, Vol 6, Issue 12
Abstract
Ebola virus disease is one of the most deadly ailments known to mankind due to its high mortality rate (up to 90%). Ebola hemorrhagic fever is an infectious disease of animal that can be transmitted to both human and non-human primates. The first epidemic of Ebola hemorrhagic fever occurred in 1976 in the Democratic Republic of the Congo. The incubation period of Ebola is less than 21 days. Ebola virus infections are depicted by immune suppression and a systemic inflammatory response that leads to damage of the vascular, coagulation and immune systems, causing multi-organ failure and shock. Five genetically distinct members of the Filoviridae family responsible for Ebola hemorrhagic fever are as follows: Zaireebolavirus, Sudan ebolavirus, Tai Forest ebolavirus, Bundibugyo ebolavirus and Restonebolavirus. The ongoing 2014 West Africa Ebola epidemic has been considered as the most serious panic in the medical field with respect to both the number of human cases and death toll. The natural host for Ebola virus is unknown, but on the basis of evidence and the nature of similar viruses, researchers believe that the virus is animal-borne and that bats are the most likely reservoir. The Ebola virus infection provides little chance to develop acquired immunity causing rapid progression of the disease. It is pertinent to mention that at present, there is no antiviral therapy or vaccine that is helpful against Ebola virus infection in humans.
Authors and Affiliations
Gajendra Vasu
Keywords
Related Articles
- EP ID EP674628
- DOI -
- Views 176
- Downloads 0
COLON TARGETED MICROBEADS: A NOVEL APPROACH IN NDDS
In oral colon-specific drug delivery system, colon has a large amount of lymphoma tissue (facilitates direct absorption in to the blood), negligible brush boarder membrane activity, and much less pancreatic enzymatic act...
THE INTERCONNECTION BETWEEN CELL PHONE USAGE AND EAR PROBLEMS AMIDST MEDICAL STUDENTS, TAIBAH UNIVERSITY
Background: Concerns regarding the potential physiological effects of exposure to radio frequency (RF) radiation have been increased recently. Objective: This study explores a relationship between the use of mobile phone...
REVIEW OF EUPHORBIA NERIIFOLIA AND THEIR OTHER SPECIES
Now a day’s focus on plant research has increased all over the world. Plants have always been an asset as being used as medicinal plants for the treatment of various diseases. One such plant is Euphorbia neriifolia with...
EFFECTS OF HONEY SUPPLEMENTATION ON CHILDREN WITH IDIOPATHIC DILATED CARDIOMYOPATHY: A RANDOMIZED SINGLE BLINDED CONTROLLED STUDY
Objectives: Evaluation of the effects of 12-weeks honey consumption on the echocardiographic parameters of children with idiopathic dilated cardiomyopathy (IDCM). Design: This study was a randomized controlled study, whi...
TO CREATE AWARENESS AMONG THE PEOPLE ABOUT ILL EFFECTS OF FREQUENT USE OF MEDICATION
Objective: The main objective of this article is to create awareness among the people of modern world about ill effects of frequent use of medication. Summary: The frequent intake of drugs in the form of medications may...