A REVIEW ON FUNCTIONALITY ASSESSMENT OF MULTIFUNCTIONAL EXCIPIENTS
Journal Title: International Journal of Pharmaceutical Sciences and Research (IJPSR) - Year 2019, Vol 10, Issue 9
Abstract
Multifunctional excipients are class of excipients that includes pre-processed and co-processed excipients that provide added functionalities to the formulation. Functionality is a desirable property of the material that aids manufacturing and improves the quality and performance of the material. This review article reveals with the functionality evaluation of excipients that include surrogate functionality and explicit functionality of excipient. The surrogate functionality gives information that predicts whether or not a particular excipient is likely to have the requisite functionality to produce a product that will meet finished product specifications in all respects. The explicit functionality means the ability of excipient to develop an appropriate formulation of a drug and a useful manufacturing process to create a tablet. Compactibility of excipient is a capability of the material to form coherent agglomerates after compression, has been analyzed by compact density, tensile strength, solid fraction, bonding index, etc. The compatibility mainly depends upon the material property like plastic and elastic.
Authors and Affiliations
S. B. Sandhan et al.
Keywords
Related Articles
- EP ID EP627073
- DOI 10.13040/IJPSR.0975-8232.10(9).4078-89
- Views 102
- Downloads 0
IN-SILICO MOLECULAR DOCKING ANALYSIS OF ISOLATED HOMOISOFLAVANONES FROM BULBS OF LEDABOURIA REVOLUTA AS GABAA RECEPTOR INHIBITORS
γ-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the vertebrate central nervous system (CNS); it activates the GABAA receptors that play a role in epilepsy. Targeting GABAA receptors through specifi...
MICROWAVE ASSISTED EXTRACTION OF BIOLOGICAL COMPONENTS OF CROCUS SATIVUS WITH DNA BARCODING TECHNOLOGY
Saffron is derived from the flower of Crocus sativus as a dried stigma. Kashmiri saffron is the most expensive herb and in sky-scraping demand by herbal and pharmaceutical industries due to which the illegal trade is pre...
EFFECT OF PHARMACIST DIRECTED COUNSELLING SERVICES ON KNOWLEDGE, ATTITUDE, AND PRACTICE (KAP) AND BLOOD PRESSURE CONTROL IN HYPERTENSIVE PATIENTS: A RANDOMIZED CONTROL TRIAL
Pharmacists play a vital role in providing counseling to the hypertensive patients to understand disease, risk factors, medications, and non-pharmacological measures required in controlling Blood Pressure (BP). This stud...
EFFECTS OF USING DIFFERENT LEVELS OF CHROMIUM PICOLINATE ON PERFORMANCE, SOME BLOOD BIOCHEMICAL AND INTESTINAL MORPHOLOGY AND MICROFLORA IN ROSS 308 BROILER CHICKS EXPOSED TO THE HEAT STRESS CONDITION
This study was aimed to investigate the effects of different levels of dietary chromium picolinate (CrPic) on performance, some blood biochemical and intestinal morphology and microflora in Ross 308 broiler chicks. A tot...
COMPARATIVE ACUTE AND SUB-ACUTE TOXICITY STUDY OF HYDRO-ALCOHOLIC EXTRACTS OF CENTELLA ASIATICA AND EVOLVULUS ALSINOIDES IN SWISS ALBINO MICE
In this study, the in-vivo toxicity of Centella asiatica & Evolvulus alsinoides were evaluated by acute and sub-acute toxicity assays according to the guidelines of OECD 423 & 407 respectively. For LD50 evaluation, a sin...