A REVIEW ON IMMEDIATE RELEASE DRUG DELIVERY SYSTEM BY USING DESIGN OF EXPERIMENT
Journal Title: Journal of Drug Discovery and Therapeutics - Year 2013, Vol 1, Issue 12
Abstract
Tablet is the most popular among all dosage forms existing today because of its convenience of self administration, compactness and easy manufacturing; Sometimes immediate onset of action is required than conventional therapy in many cases. Tablets are the most popular dosage form because of its unique properties such as ease of administration, low cost and non-invasive therapy etc .Therapeutic success of any therapy depends on the patient’s compliance toward the therapy. As a drug entity nears the end of its patent life, it is common for pharmaceutical manufacturers to develop a given drug entity in a new and improved dosage form. To provide the patients with the most convenient mode of administration, there was a need to develop immediate release dosage form, particularly one that disintegrates rapidly and disperses and helps in enhancing stearate. Immediate drug release dosage forms disintegrate rapidly after administration with enhanced rate of dissolution. Direct compressed method was adapted to prepare the tablets by using different excipient microcrystalline cellulose, lactose, pregelatinized starch, croscarmellose sodium, talc, sodium starch glycolate, magnesium. A new dosage form allows a manufacturer to extend market exclusivity, while offering its patient population a more convenient dosage form or dosing regimen.
Authors and Affiliations
Manish Jaimini*| Department of Pharmaceutics, Jaipur College of Pharmacy, Sitapura, Jaipur, affiliated to Rajasthan University of Health Sciences, Jaipur, Rajasthan, India., Sonam Ranga| Department of Pharmaceutics, Jaipur College of Pharmacy, Sitapura, Jaipur, affiliated to Rajasthan University of Health Sciences, Jaipur, Rajasthan, India., Amit Kumar| Department of Pharmaceutics, Jaipur College of Pharmacy, Sitapura, Jaipur, affiliated to Rajasthan University of Health Sciences, Jaipur, Rajasthan, India., Sanjay Kumar Sharma| Department of Pharmaceutics, Jaipur College of Pharmacy, Sitapura, Jaipur, affiliated to Rajasthan University of Health Sciences, Jaipur, Rajasthan, India., Bhupendra Singh Chauhan| Department of Pharmaceutics, Jaipur College of Pharmacy, Sitapura, Jaipur, affiliated to Rajasthan University of Health Sciences, Jaipur, Rajasthan, India.
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