A REVIEW ON LIQUISOLID TECHNOLOGY
Journal Title: Int J of Pharm Rev& Res - Year 2015, Vol 5, Issue 3
Abstract
The “Liquisolid” technique is a novel and capable addition towards such an aims for solubility enhancement and dissolution improvement, thereby it increases the bioavailability. This technique is based upon the admixture ofdrug loaded solutions with appropriate carrier and coating materials. Formulation concept of liquisolid technology involves water insoluble drugs dissolved in suitable non-volatile liquid vehicles, and converted in to compact by blending with selective powder excipients. The use of non-volatile solvent causes improved wettability and ensures molecular dispersion of drug in the formulation and leads to enhance solubility. The liquisolid technology allows the transformation of liquid systems into solid drug delivery systems such as tablets. The liquisolid approach has been successfully applied in release enhancement of low dose poorly soluble drugs.
Authors and Affiliations
A. Swarupa , J. V. C Sharma , P. Vishnu Priya , Shyamala
Keywords
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