A Review on Lorcaserin – A Selective 5-HT Serotonin Receptor Agonist in Obesity Management
Journal Title: International Journal of Current Research and Review - Year 2017, Vol 9, Issue 17
Abstract
Lorcaserin is a novel anti-obesity agent. The study retrospect’s the pharmacokinetic effects, mode of action, adverse drug reactions and various uses of Lorcaserin. Lorcaserin is pro-opiomelanocortin neurons stimulator present in the nucleus of hypothalamus resulting in a peak melacortin-4 receptor activity, which results in satiety and decreased food intake. Though some side effects were reported, the potential benefits of Lorcaserin outweigh the risks. Serum drug monitoring is not required. Lorcaserin is a 5HT2C receptor agonist whose property may also be studied to treat anxiety, Alzheimer’s disease, depression and parkinsonism. Literature review was conducted to identify relevant studies. The study reviewed the pharmacokinetics, pharmacodynamics and clinical trials proposed so far on lorcaserin.
Authors and Affiliations
Dr. C. Vinodhini
Keywords
Related Articles
- EP ID EP608897
- DOI 10.7324/IJCRR.2017.9176
- Views 90
- Downloads 0
Hemorrhagic risks associated with dental procedure in a rare case of Type II Sturge weber syndrome
Aim: Sturge weber syndrome (SWS) is a sporadic congenital neurocutaneous disorder. It belongs to phakomatoses group of disorders. It is basically combinations of manifestations such as port-wine stains (PWS) of the face,...
Spectrum of Non-neoplastic Skin Lesions: A Histopathological Study based on Punch Biopsy
Introduction: Accurate diagnosis of skin is of utmost importance for management of different skin disorders presenting with the similar clinical signs and symptoms. Therefore to confirm the diagnosis and start treatment...
Amlodipine - A Novel Offender of Gingival Overgrowth–A Case Report
Aim: There are only few cases presented with Amlodipine induced gingival enlargement so far. The main purpose of this case report is to discuss about Amlodipine-influenced gingival enlargement in a 56 years old female hy...
Growth Promoting and Probiotic Potential of the Endophytic Bacterium Rhodococcus globerulus colonizing the Medicinal Plant Plectranthus amboinicus (Lour.) Spreng
Objectives: It was intended to isolate endophytic bacteria from Plectranthus amboinicus leaves to elucidate the plant growth promotion potential. Methodology: Phytochemical constituents of Plectranthus amboinicus leaves...
Mathematical Model on two layer Blood Flow in capillaries with context to Diabetes
In this paper the review of mathematical modeling of two phase blood flow in capillary is done with disease Diabetes .There are two phase of blood flow, one is RBC and other one is plasma. By the Fahreaus-Lindqvist influ...