A REVIEW ON NANOCOCHLEATES NOVEL APPROACH FOR DRUG DELIVERY
Journal Title: WORLD JOURNAL PHARMACY AND PHARMACEUTICAL SCIENCE - Year 2018, Vol 7, Issue 7
Abstract
Nanocochleate is a novel drug delivery system which have ability to enacapsulate the water soluble cationic drugs as well as hydrophobic and hydrophilic drugs. This nanotechnology is use encapsulate drug which have cationic and anionic nature and that possess poor oral bioavailability. Nanocochleates are lipid based supramolecular assemblies made from natural product anionic phospholipid and divalent cation Main purpose of development of the nanocochleate drug delivery to improve therapeutic efficacy of therapeutic active agent. Nanocochleate is a lipid based drug delivery in the liposomal vesicles is convert in to nanocochleate by action of calcium divalent cation. Nanocochleates technology also use encapsulation of anticancer agent because of anticancer agent have low oral bioavailability and also have low solubility and low permeability.
Authors and Affiliations
Sangita Talke
Keywords
Related Articles
- EP ID EP627548
- DOI -
- Views 132
- Downloads 0
ANTIMICROBIAL ACTIVITY OF ARTOCARPUS ALTILIS, (BREADFRUIT), AVERRHOA BILIMBI (SOURIE) AND CORDIA CURASSAVICA (BLACKSTAGE) STEM EXTRACT AGAINST STREPTOCOCCOUS MUTANS, IN PURSUIT OF NATURAL ANTICARIES AGENTS
The antibacterial activity of three plant extracts: Artocarpus altilis fruit and leaves (Breadfruit), Averrhoa bilimbi (Sourie) fruit and leaves and Cordia Curassavica (Blackstage) stem and leaf extracts were evaluated a...
STABILITY STUDY OF ESOMEPRAZOLE PREPARATIONS IN DIFFERENT PACKAGING MATERIAL USING STABILITY INDICATING VALIDATED HPLC METHOD
A stability study of esomeprazole was carried out in accordance with the guideline for Industry Q1A(R2): Stability Testing of New Drug Substances and Products.[1] Esomeprazole is sensitive to heat, humidity, and light, c...
EFFECT OF TEMPERATURE OF WATER USED FOR RECONSTITUTION ON STABILITY OF ANTIBIOTIC DRY SUSPENSION
This study is carried out to test the stability of antibiotic dry suspensions reconstituted with various water temperatures. The testing included physical, microbial and chemical changes of samples reconstituted with wat...
SYNTHESIS AND SPECTRAL CHARACTERIZATION OF SOME NEW PYRAZOLINE DERIVATIVES
The title compounds were synthesized by condensation azachalcones with ethylacetoacetate to get intermediate 3-(pyridyl)-5-aryl-6- ethylcarboxylate-2-cyclohexenone which were subsequently treated with hydrazine hydrate t...
ANTI-OBESITY DRUGS OF KAIDEVA NIGHANTU: A LITERARY SURVEY
Obesity is a blessing of the modern age of machines and materialism. Globally, there are more than one billion overweight adults out of them more than 300 million are clinically obese. Individual habits with stressful li...