A review on nanoparticles – preparation and evaluation parameters
Journal Title: Indian Journal of Pharmaceutical and Biological Research - Year 2016, Vol 4, Issue 2
Abstract
Nanotechnology defined as a tiny science. Design characterization, production and applications of structures, devices and systems by controlling shape and size at nanometer scale is refers to nanotechnology. Nanotechnology by which we can achieve better therapeutic action, better bioavailability and better patient compliance. Several nanoformulations are successfully used for brain delivery which includes nanoparticles system (polymeric/solid lipid), liposomes, dendrimer‟s, nanoemulsions, nanosuspension and ligand mediated nanosystems.Nanoparticles are defined as particulate dispersions or solid particles drug carrier that may or may not be biodegradable. Several techniques are used for preparation of nanoparticles like Solvent Evaporation, Double Emulsification method, Emulsions - Diffusion Method, Nanoprecipitation, Coacervation method, Salting Out Method, Dialysis and Supercritical fluid technology. Nanoparticles are subjected to several evaluation parameters such as yield of nanoparticles, Drug Content / Surface entrapment / Drug entrapment, Particle Size and Zeta Potential , Surface Morphology, Polydispersity index, In-vitro release Study, Kinetic Study, Stability of nanoparticles.
Authors and Affiliations
RENU TIRUWA| Department of Pharmaceutics, Division of Pharmaceutical Sciences, Shri guru ram rai institute of technology and science, Patelnagar Dehradun, Uttarakhand, India
Keywords
Related Articles
- EP ID EP15500
- DOI -
- Views 351
- Downloads 28
Antimicrobial Screening of Some capparidaceous Medicinal Plants of North-West Rajasthan
Antimicrobial screening of ethyl ether and alcoholic extracts of leaves of three selected medicinal plant species of capparidaceae family growing in North–Western Rajasthan was carried out. Capparis decidua, Cleome g...
Evaluation of Nutritional value of Mollugo cerviana Ser. growing wild in Bikaner District of Rajasthan
Plants of arid and semiarid zones are good source of phytochemically important compounds. Mollugo cerviana is a common wild plant of Bikaner and surrounding areas and it has been evaluated for the nutritive contents from...
Synthesis and antimicrobial activity of some newer semicarbazone analogues
On the basis of literature review Semicarbazones have been potent in activities such as antifungal, antibacterial, antituberculosis, anticancerous etc. Till date various works has been done however still there is tremend...
A review on recent innovation in osmotically controlled drug delivery system
In recent years, oral controlled release (CR) system is most acceptable dosage form by the patients. Drugs having short biological half-life and poor water solubility are the suitable candidate for development of CR sy...
Stability indicating RP-HPLC method development and validation for the simultaneous determination of Sofosbuvir and Velpatasvir in tablet dosage forms
Stability indicating RP-HPLC method was developed for the simultaneous quantitation of Sofosbuvir and Velpatasvir in its pharmaceutical dosage form and validated. The drugs were separated on Discovery C18 (150mm x 4.6mm,...