A review on nanoparticles – preparation and evaluation parameters
Journal Title: Indian Journal of Pharmaceutical and Biological Research - Year 2016, Vol 4, Issue 2
Abstract
Nanotechnology defined as a tiny science. Design characterization, production and applications of structures, devices and systems by controlling shape and size at nanometer scale is refers to nanotechnology. Nanotechnology by which we can achieve better therapeutic action, better bioavailability and better patient compliance. Several nanoformulations are successfully used for brain delivery which includes nanoparticles system (polymeric/solid lipid), liposomes, dendrimer‟s, nanoemulsions, nanosuspension and ligand mediated nanosystems.Nanoparticles are defined as particulate dispersions or solid particles drug carrier that may or may not be biodegradable. Several techniques are used for preparation of nanoparticles like Solvent Evaporation, Double Emulsification method, Emulsions - Diffusion Method, Nanoprecipitation, Coacervation method, Salting Out Method, Dialysis and Supercritical fluid technology. Nanoparticles are subjected to several evaluation parameters such as yield of nanoparticles, Drug Content / Surface entrapment / Drug entrapment, Particle Size and Zeta Potential , Surface Morphology, Polydispersity index, In-vitro release Study, Kinetic Study, Stability of nanoparticles.
Authors and Affiliations
RENU TIRUWA| Department of Pharmaceutics, Division of Pharmaceutical Sciences, Shri guru ram rai institute of technology and science, Patelnagar Dehradun, Uttarakhand, India
Keywords
Related Articles
- EP ID EP15500
- DOI -
- Views 334
- Downloads 28
Antimicrobial Screening of Some capparidaceous Medicinal Plants of North-West Rajasthan
Antimicrobial screening of ethyl ether and alcoholic extracts of leaves of three selected medicinal plant species of capparidaceae family growing in North–Western Rajasthan was carried out. Capparis decidua, Cleome g...
In-Silico Drug Design: A revolutionary approach to change the concept of current Drug Discovery Process
Computational methods play a central role in modern drug discovery process. It includes the design and management of small molecule libraries, initial hit identification through virtual screening, optimization of the a...
Evaluation of Vitamin B1, B2 and B6 Tablets in Bangladesh by UV-Vis Spectrophotometer
Thiamine hydrochloride (vitamin B1), riboflavin (vitamin B2) and pyridoxine hydrochloride (vitamin B6) were assayed in pharmaceutical dosages form. Thiamine hydrochloride of 100 mg dose of six different companies, ribofl...
Fast dissolving tablets: a novel approach
An oral route of drug administration is the most popular route of administration. It have wide acceptance up to 50-60% of total dosage forms. Tablet is the most popular dosage forms existing today because of its conven...
Development and Validation of RP-HPLC method for Simultaneous Estimation of Metformin and Pioglitazone
A new simple, accurate ,precise and reproducible RP-HPLC method has been developed for simultaneous estimation of metformin and pioglitazone in bulk drug form using proper HPLC system. The mobile phase consists of phosph...