A Review on Neurophysiologic and Immunobiochemical Aspects of Tick Paralysis
Journal Title: Nepal Journal of Neuroscience - Year 2009, Vol 6, Issue 2
Abstract
From as early as 1550 B.C. to present time, “Tick fever” has been reported worldwide. There has been demonstration and review of tick paralysis caused by 64 species of ticks belonging in different genera. All the lifecycle stages of ticks can produce neurotoxin and cause paralysis especially in the young animals of the larger species and in all ages and sizes of the pet species and humans. Tick paralysis is a neurological syndrome that is frequently confused with other acute disorders. Experimental studies indicate that the toxin may produce a substantial decrease in maximal motor nerve conduction velocities. It is easy to be recovered from normal tick paralysis by removing the ticks from body. The study of vaccination against ticks and tick paralysis needs to be conducted on the basis of in vitro and in-vivo studies coupled with neurophysiology and immunobiochemistry.
Authors and Affiliations
Tirth Raj Ghimire, MSc, Ph. D
Keywords
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