A REVIEW ON THE VARIOUS BIOLOGICAL ACTIVITIES OF THIADIAZOLE

Abstract

Thiadiazole and their derivatives have been studied colossally because of their wide range of biological activity. They are found to be effectual as antibacterial, antimalarial, antiviral, antiinflammatory, anticancer and antianthelminthic agents. Distinct biological activities, such as antibacterial, anti-inflammatory, and antiviral have been consort with 1, 3, 4-thiadiazole derivatives. The substituted 1, 3, 4 Thiadiazole nucleus is particularly ubiquitous, and found in some marketed drugs such as acetazolamide, Methazolamide and antibacterial such as Sulphamethazole, antibiotic like Cefazoline. The synthesis of 1, 3, 4 Thiadiazole derivatives has allured widespread attention due to their diverse biological activities, including antimicrobial, anti-inflammatory, analgesic, and antianthelmintic. These reviews focused on various biological activities consorted with thiadiazole nucleus. 

Authors and Affiliations

Neetu . , Dinesh Mehta, Poonam Taya

Keywords

Related Articles

ANTIOXIDANT ACTIVITY AND ANTIBACTERIAL SCREENING OF TUBERS OF AMORPHOPHALLUS KONKANENSIS AND AMORPHOPHALLUS BULBIFER (ARACEAE)

Objective: Antioxidant activity (AOA) and antibacterial screening of tubers of unexplored Amorphophallus konkanensis Hett., Yadav & Patil (AKT) and Amorphophallus bulbifer (Roxb.) Bl. (ABT).Methods: Antioxidant activ...

DISEASE PREVENTION FUNCTIONAL FOODS FROM THE HIGH POTENTIAL MMP-2 INHIBITION ACTIVITY OF PINEAPPLE JUICE GRANULE

Objective: This study aimed to compare total phenolic acid and protein contents as well as free radical scavenging, enzyme activities of fresh and fermented pineapple juice. Methods: The dried pineapple juice, prepared...

SYNTHESIS, ANTICANCER EVALUATION AND MOLECULAR MODELING OF SOME SUBSTITUTED THIAZOLIDINONYL AND THIAZOLYL PYRAZOLE DERIVATIVES

Objective: The present work aimed to synthesize some new substituted thiazoles incorporated to pyrazole moiety starting from 1-(3-chlorophenyl)-3-(4-methoxyphenyl)-1H-pyrazole-4-carboxaldehyde (1) in order to evaluate th...

ANTICANCER AND ANTIOXIDANT ACTIVITY OF METHANOL EXTRACT OF HIPPOPHAE SALICIFOLIA IN EAC INDUCED SWISS ALBINO MICE

Objective: Anticancer activity of methanol extract of Hippophae salicifolia (MEHS) bark was evaluated using the Ehrlich Ascites Carcinoma (EAC) cells on Swiss albino mice.Methods: In vitro cytotoxicity assay has been eva...

PRESCRIPTION PATTERN ANALYSIS OF ANTI-INFLAMMATORY DRUGS IN GENERAL MEDICINE AND SURGERY DEPARTMENT AT A TERTIARY CARE HOSPITAL

Objective: The objective of this research was to evaluate and analyze the prescription pattern of anti-inflammatory drugs given in the general medicine and surgery department at a tertiary care hospital.Methods: The enti...

Download PDF file
  • EP ID EP578842
  • DOI -
  • Views 72
  • Downloads 0

How To Cite

Neetu . , Dinesh Mehta, Poonam Taya (2015). A REVIEW ON THE VARIOUS BIOLOGICAL ACTIVITIES OF THIADIAZOLE. International Journal of Pharmacy and Pharmaceutical Sciences, 7(4), 39-47. https://europub.co.uk/articles/-A-578842