A Rhinofacial Conidiobolus coronatus Fungal Infection Presenting as an Intranasal Tumour
Journal Title: Sultan Qaboos University Medical Journal - Year 2018, Vol 1, Issue 4
Abstract
Conidiobolomycosis is a rare fungal infection that affects adults in tropical regions. We report a 42-year-old male patient who was referred to the Sulaiman Al Habib Hospital, Dubai, United Arab Emirates (UAE), in 2013 with excessive nasal bleeding and a suspected nasal tumour. He reported having briefly visited central India nine months previously. Computed tomography and magnetic resonance imaging showed a highly vascularised mass in the nasal cavity. However, after surgical excision, initial treatment with amphotericin B deoxycholate was unsuccessful and the disease progressed, leading to external and internal nasal deformation and necessitating further excision and facial reconstruction. Histopathological analysis of the second biopsy revealed Splendore-Hoeppli changes consistent with a fungal infection. Microbiological findings subsequently confirmed Conidiobolus coronatus. Subsequently, the patient was successfully treated with a combination of itraconazole and fluconazole. To the best of the authors’ knowledge, this is the first report of a case of rhinofacial conidiobolomycosis from the UAE.
Authors and Affiliations
Levente Deak, Savitha Mudalagiriyappa, Annelyse Ballin, David Saxton, Arunaloke Chakrabarti
Keywords
Related Articles
- EP ID EP37489
- DOI http://dx.doi.org/10.18295/squmj.2018.18.04.022
- Views 335
- Downloads 0
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