A Serological Study of Blood Borne Viral Hepatitis Cases Attending IIMS & R, Lucknow
Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 3
Abstract
Context: Acute viral hepatitis (AVH) is a major public health problem and is an important cause of morbidity and mortality. Aim: To study the prevalence of viral Hepatitis B and Hepatitis C cases in patients attending IIMS&R, Lucknow, U.P. Material &Method: Blood samples and clinical information was collected from cases of over a 6 month period (1st January 2015 to 30th June 2015). Samples were tested for Hepatitis B surface antigen, antiHCV total antibodies. Statistical Analysis Used: Fisher’s exact test was used and a P < 0.05 was considered to be statistically significant. Results: The prevalence rate was found to be 4.5% in HBV and 2.5% for HCV .Out of 1434 patients 66 were Hepatitis B positive and 35 were Hepatitis C virus.57.6% of the patients of Hepatitis B and 31.4% of hepatitis C were males. On comparing both HBV and HCV positive viral infections, statistically significant values (p≤ 0.05) were found in males. About three fourth (76.9%) of the patients of hepatitis B and 62.9% of HCV were found to be literate and belonged to lower and middle socio-economic status having poor hygiene .Statistically significant values were observed in low socio-economic status (p≤.003) , literacy level (p≤ 0.01) , serum bilirubin (p=0.005) and alkaline phosphate (p=0.002) between Hepatitis B and C patients was observed . The results of ELISA test were 100% while for Rapid card test it was 95% only Conclusion: Preventive measures should include health education regarding parentral transmission of infection stringent blood banking laws need to be introduced and use of disposable syringes/needles should be made mandatory. Reuse of needles, shaving kits and razor blades should be discouraged. Universal immunization of all infants is desirable to decrease the carrier pool and it is inferred from the present study that Hepatitis B immunization should begin at birth to have greater impact.
Authors and Affiliations
Karuna Dubey
Keywords
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