A Simple Computed Tomography Scoring System to Predict Histological Malignancy of Solitary Fibrous Tumors of the Pleura
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2015, Vol 5, Issue 10
Abstract
Purpose: The aim of the present study was to define the very first score enabling discrimination between benign and malignant solitary fibrous tumors of the pleura (SFTPs), on the basis of reliable preoperative CT features. Methods: Between December 2004 and November 2012, 56 patients underwent complete resection for SFTP at six institutes. CT scans were reviewed retrospectively, and a diagnostic scoring system for predicting malignant SFTP preoperatively was designed. Results: Univariate analysis revealed seven significant predictors of malignant SFTP: tumor size ≥ 10 cm (p=0.002), tumor heterogeneity spontaneously (p=0.019) or after contrast medium injection (p=0.029), existence of intratumoral fluid density areas (p=0.011), a pleural effusion (p=0.01), measurable (diameter >1 mm) intratumoral vessels (p=0.019), a hypervascular character (visible intratumoral vessels and/or intense enhancement) (p=0.001). A scoring system based on these seven CT features, each assigned 1 point, and with a cut-off of 4 points, could predict malignant SFTP with a specificity of 85% and a sensitivity of 48%. Conclusion: Our scoring system using seven CT features (tumor size ≥ 10 cm, tumor heterogeneity with or without contrast injection, intratumoral fluid density areas, pleural effusion, measurable intratumoral vessels, and a hypervascular character of the tumor) may be helpful for predicting histological malignancy of solitary fibrous tumors of the pleura.
Authors and Affiliations
Siegfried Hélage, Marie-Pierre Revel, Marco Alifano, Audrey Mansuet-Lupo, Dominique Vadrot
Keywords
Related Articles
- EP ID EP347201
- DOI 10.9734/BJMMR/2015/13958
- Views 74
- Downloads 0
Hepatitis C Virus Infection, Metabolic Disorders and Non-alcoholic Fatty Liver Disease: A Literature Review
Aims: Non-alcoholic fatty liver disease (NAFLD) is a prevalent metabolic disorder both in industrialized and developing countries that makes a large health and financial burden to the patients and the society. In the cur...
Tuberculosis in an HIV-infected Child in a Developing Country: A Case Report of Diagnosis Challenges
Aims: To highlight the challenges and the diagnostic dilemmas in resource restricted settings to diagnose and treat Tuberculosis (TB), especially when it co-exists with Human immunodeficiency virus (HIV) infection. Pres...
HIV/AIDS Recovery Rates in Male and Female Patients, Treated with Medicinal synthetic Aluminum-magnesium silicate
Aim: Clinical trial of antiretroviral efficacy of Medicinal synthetic Aluminum-magnesium silicate (MSAMS) in male and female patients. Methodology: HIV/AIDS patients were classified as, male-patients and female-patients....
Tube Caecostomy: A Veritable Alternative in the Surgical Treatment of Advanced Appendicitis
Background: Advanced appendicitis poses a serious challenge to surgeons in poor resource settings and it is associated with a higher morbidity and mortality. Objective: To report the outcome of tube-caecostomy in the pre...
The Use of Magnification and Work Posture in Dentistry – A Literature Review
Background: Loupes represent a type of magnification and their use can promote higher quality on dental treatment. Besides those advantages magnification can be beneficial for musculoskeletal health maintenance on dental...