A study Antiurolithiatic Activity of ethanolic extract of Asparagus racemosus in animal models
Journal Title: International Journal of Pharmacological Research - Year 2015, Vol 5, Issue 11
Abstract
Objective: To investigate the Antiurolithiatic Activity of ethanolic extract of Asparagus racemosus in animal models. Materials and Methods: The study includes performing on healthy albino rats of either sex weighing 220 270gms and urolithiasis was induced by oral administration of ethylene glycol and ammonium chloride water. The parameters studied are serum analysis for Urea, Creatinine, Calcium and Phosphorus, Body Weight of animals included in the study group and Histopathological Study of kidney for the presences crystals. Results In our study the Ethanolic extract of Asparagus Racemosus with doses of 800mg/kg and 1600mg/kg per orally to rats showed significant reduction in serum urea, creatinine, calcium and phosphorus levels in urolithiatic rats when compared to the positive control rats (Group II). These results were found to be statistically significant (p<0.05). Conclusion: Ethanol Extract of Asparagus racemosus has a significant antiurolithiatic activity.
Authors and Affiliations
Jagannath N, Asha P. Dass, Khasif Ahmed
Keywords
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- EP ID EP434609
- DOI 10.7439/ijpr.v5i11.2530
- Views 59
- Downloads 0
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