A Study of atherosclerotic lesions of aorta with CD4 immunostaining
Journal Title: IP Journal of Diagnostic Pathology and Oncology - Year 2018, Vol 3, Issue 1
Abstract
Indian population is affected with atherosclerosis at younger age when compared to other ethnic groups In this study histopathological grading of atherosclerotic lesions of the ascending aorta in archival specimens were performed with immunohistochemical marker for CD4 cells in each grade of atherosclerosis Mean ages of males and females in our study were 5211plusmn1579 and 4018plusmn1773 years respectively The prevalence of various grades of atherosclerosis revealed Grade 1 atherosclerosis in 490 Grade 2 in 1765 Grade 3 in 3235 grade 4 in 2843 grade 5 in 1373 cases Grade 6 was the least common grade of atherosclerosis 196 Immunohistochemistry for CD4 was performed in 18 subjects with three cases each of grade 1 to 6 CD4 was quantified higher in grade 1 and grade 2 lesions while progressive reduction in CD4 positivity was seen in the advanced lesionsKeywords Aorta Archival specimens Atherosclerosis CD4 Histopathology
Authors and Affiliations
Arasi Rajesh, Shantaraman, Johnsy Merla
Keywords
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- EP ID EP482729
- DOI 10.18231/2581-3706.2018.0007
- Views 114
- Downloads 0
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