A study of Bacterial Vaginonsis and its association with preterm labor and fetal outcome
Journal Title: Perspectives In Medical Research - Year 2016, Vol 4, Issue 2
Abstract
Introduction:Bacterial vaginosis (BV) affects 6–32% of pregnant women. BV is a risk factor for Preterm delivery and is also associated with peripartum complications such as Preterm premature rupture of membranes (PPROM), chorioamnionitis, and Postpartum endometritis. As Bacterial vaginosis in pregnancy is receiving extensive attention as a cause of preterm labour, a comprehensive prospective study was proposed to be undertaken to find out incidence of Bacterial vaginosis in preterm labour in hospital setting with simultaneous medical intervention to prevent premature birth as far as possible. Aims & Objectives: To study incidence of bacterial vaginosis in preterm and term labour, to study association of bacterial vaginosis with preterm labour (PTL) and to study perinatal outcome in bacterial vaginosis positive cases Material and Methods: Fifty women who presented with preterm labour (study group) and fifty women in labour at term (control group) admitted in the Department of Obstetrics and Gynecology, Prathima Institute of Medical sciences, Karimnagar from December 2013 to June 2015 were examined for Bacterial Vaginosis using Amsel criteria and Nugent score. Maternal age, socioeconomic status (SES), previous pregnancy outcome, onset of Preterm birth to delivery, birth weight and Apgar score were all noted. All babies of both groups followed up to first week of neonatal life. Results: The incidence of bacterial vaginosis in patients with idiopathic preterm labour was 24 percent and among term group was 8 percent. Bacterial vaginosis was significantly (P >0.05) associated with idiopathic preterm labour. Out of 16 patients who had bacterial vaginosis, 12 had preterm delivery (>37 weeks). In 84 patients without bacterial vaginosis 38 had preterm delivery. Bacterial vaginosis was significantly associated with low birth weight babies (P >0.05). Bacterial vaginosis was significantly associated with neonatal jaundice and neonatal sepsis and neonatal death. Conclusion: This study shows that BV is significantly associated with preterm birth and is one of the most important causes of PTL leading to various neonatal mortality, morbidity and even permanent disability. Also prevention of PTL in pregnant women decreases the incidence of postpartum endometritis and hence reduces maternal morbidity. Methods and materials to detect bacterial vaginosis is very simple, can be carried out as outdoor procedure. If diagnosed in the early part of pregnancy and treated with antimicrobial therapy, then perhaps we can decrease the burden of prematurity which will be great benefit for society and Nation
Authors and Affiliations
V Usha Rani
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