A study of BMI status and estrogen- progesterone receptors in patients with carcinoma of breast
Journal Title: MedPulse -International Medical Journal - Year 2016, Vol 3, Issue 3
Abstract
Introduction: Breast carcinoma is the second most common carcinoma in women and account for 22 % of all female cancer, which is more than twice the prevalence of cancer in women at any other site. Aims and Objective: To Study BMI Status and estrogen- Progesterone Receptors in Patients with Carcinoma of Breast. Methodology: This study was carried out on patients coming to the Department of Surgery in Yenepoya Medical College Hospital from October 2013 to October 2015. Around 50 patients with breast carcinoma not treated by chemotherapy, radiotherapy, and hormonal therapy were included. The clinical information like age of the patient, age of menarche, age of menopause, parity of the patient, tumor size and number of lymph nodes and BMI were collected. The statistical analysis done by Fisher Exact test. Result: Maximum people were in the age group of 45 -50yrs.The specimen from these women were send for estrogen and progesterone receptor status analysis. The mean age of the patients in the study is 48 yrs. Most of the patients with tumors were seen with BMI in the range of 18-25. Majority of which were ER Negative. There is decreasing trend of ER Negative tumors as the BMI increases (Fischer exact test and the p value is 0.025, which is significant).Most of the patients were seen in the range of 18-25. Majority of which were PR Negative. There is decreasing trend of PR Negative tumors as the BMI increases. (By Fischer exact test the p value is 0.821which is not-significant). Conclusion: BMI is more co related with ER rather than PR and there is decreasing trend of ER as BMI increases and hence disease prognosis is also decreases.
Authors and Affiliations
Syed Aezaz Quryshi, Ramdas Rai
Keywords
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