A STUDY OF CANDIDA SPECIES BLOODSTREAM INFECTIONS IN NEONATES IN A TERTIARY CARE HOSPITAL
Journal Title: International Journal of Microbiology Research - Year 2016, Vol 8, Issue 10
Abstract
Background: Fungemia due to Candida species is reported commonly and is an increasing problem especially in neonatal intensive care units (NICU). A significant increase in the number of cases of candidemia was observed from November 2015 to January 2016 in NICU of our tertiary care hospital in North Delhi. The species of Candida isolated from these cases were diverse and included C. tropicalis, C. krusei and C. parapsilosis. Methods: To investigate this increase in the cases of Non albicans Candida bloodstream infections, a microbiological study, a case control study and revision of infection control practices was performed. There were total of 8 cases of Candidemia at the time of investigation. The samples for surveillance culture were obtained from various environmental surfaces, from hands of health care workers (HCWs) and from skin and cannulas of the cases. Results: Some factors like Preterm deliveries, low birth weight (LBW), parenteral nutrition, presence of central venous catheters and premature rupture of membrane at the time of delivery, were more commonly seen in cases when compared to controls. The surveillance samples on microbiological culture did not yield any Candida isolate. Some lapses in Infection control practices were observed and with the strict enforcement of infection control measures, the progress of this increase in the number of cases of Cndidemia could be halted. Conclusion: it was therefore concluded that Candidemia was associated with previously described risk factors and that it is the interplay of host, environment and pathogen which contributed to increase in the number of cases of Candidemia in our hospital.
Authors and Affiliations
S. SATIJA, D. K. BHAGWANI, M. SHARMA, N. SHREE
AVAILABILITY AND REQUIREMENTS OF MAJOR FOOD ITEMS IN NEH REGIONS: AN EMPIRICAL ANALYSIS
The present study aims to find out food and nutritional security in North- East region of India by simple tabular method during 2001 to 2011 period. The study found that NE region according to demand deficient in product...
MICROBIAL COMMUNITY COMPOSITION IN CONTAMINATED SOIL SAMPLES OF THE YAMUNA RIVER
Yamuna is one of the important river of India and its stretch through Delhi is its most polluted part. Therefore it is important to study the effects of pollutants on microbial community structure to restorate it. For bi...
SYNTHESIS, CHARACTERIZATION AND SCREENING OF THIAZOLIDINE-2,4-DIONE DERIVATIVES AS ANTIMICROBIAL AGENTS
Thiazolidine-2,4-dione derivatives (4a-4e) have been synthesized and characterized by physico-chemical, elemental (C,H,N,S), FT-IR, mass and 1HNMR spectral analysis. In this context, the aim was to synthesized thiazolidi...
ANTIMICROBIAL RESISTANCE PATTERN OF ENTEROCOCCUS SPECIES WITH SPECIAL REFERENCE TO VANCOMYCIN RESISTANCE
Background: Enterococci are an important cause of hospital acquired infection and have become progressively more resistant to antibiotics. Vancomycin resistant enterococci are emerging as an important problem in hospital...
PROBIOTICS AND PREBIOTICS
Probiotics and prebiotics are a special class of food products as their application in wellness of human beings is well established. Probiotics are living microorganisms that are taken as dietary supplements while prebio...