A Study of clinical profile, disease severity and treatment response of Movement disorders at a tertiary care teaching hospital

Journal Title: International Journal of Medical Research and Review - Year 2018, Vol 6, Issue 1

Abstract

Background: Movement disorders are one of the common neurological problems seen by General physicians and neurophysicians. The clinical phenotype of Movement disorders is variable. Aim of the study: The objective of the study was to study the clinical profile, disease severity and treatment response of Movement disorders at a tertiary care teaching hospital. Results: The present study was a prospective observational study comprising 55 clinically detectable patients of movement disorders. Out of fifty-five, the frequency of various Movement disorders were as follows: Parkinson’s disease- 25 (45.5%), Wilson`s disease (WD)-9 (16.36%), Progressivesupranuclear palsy- 8(14.54%), Essential Tremor with Parkinson disease 5 (9.0%), Choreiform disorders- 5(9.0%). Mean MDS-UPDRS Part III score in OFF stage of PD was 57.7±13.2 and in ON stage was 28.2±10.2 suggesting significant improvement. Seventy-six percentages of PD patients had Good response to Dopaminergic agonists and Levodopa administration, while better response was seen in WD, ET+PD and the poor response in PSP patients respectively. Conclusion: Identifying and describing the clinical phenomenology of Movement disorders is the first step in the diagnostic evaluation of the patients as against to the localization in General Neurological disorders. Disease severity scales do assess the progression of the disease at the earliest and there are affordable regimes of various medications are available to treat them at the earliest, so as to reduce the morbidity and to increase health related quality of life.

Authors and Affiliations

Shaik Afsar Pasha, Phanibhushan Phanibhushan, T. V. Pavan Kumar, B. Bhaskara Rao, Shaik Arif Pasha

Keywords

Related Articles

Pathological findings associated with stillborn babies

Introduction: Fetal death rate and Perinatal Mortality rate are important indicators of a country’s Health care system. Stillbirth forms a prime contributing factor in deciding these rates. But the causes of Stillbirth a...

Role of Estimation of Serum Ferritin, Vitamin B12 and Folic Acid in Management of Beta Thalassemic Children

Objective: To estimate the levels of serum Ferritin, Vitamin B12 and Folic acid in beta thalassemic children. Introduction: Beta thalassemia is the most common genetically transmitted haematological disorder in Indian ch...

Outcome after Interlocking intramedullary nailing of humeral shaft fractures

Introduction: Management of fractures of humeral shaft is always a challenging problem to deal with as they are very frequently associated with multiple injuries, leading to complications. Interlocking intramedullary nai...

A case report on and chronic calcific pancreatitis primary systemic amyloidosis with symptomatic gastric involvement

Systemic amyloidosis is a disorder characterized by extracellular deposition ofamyloid in various organs and tissues including the gastrointestinal tract, kidney, heart, and liver.Gastric involvement occurs in 8–12% of p...

Comparative study of recurrence after pterygium excision with conjunctival autografting and amniotic membrane transplantation

Introduction: Pterygium is ocular surface lesion thought to originate from damage to limbal stem cells by chronic ultra violet light exposure. It has high recurrence rates following resection. Both amniotic membrane and...

Download PDF file
  • EP ID EP344451
  • DOI 10.17511/ijmrr. 2018.i01.03
  • Views 152
  • Downloads 0

How To Cite

Shaik Afsar Pasha, Phanibhushan Phanibhushan, T. V. Pavan Kumar, B. Bhaskara Rao, Shaik Arif Pasha (2018). A Study of clinical profile, disease severity and treatment response of Movement disorders at a tertiary care teaching hospital. International Journal of Medical Research and Review, 6(1), 10-17. https://europub.co.uk/articles/-A-344451