A STUDY OF CLINICAL PROFILE OF PATIENTS WITH NEW ONSET ALCOHOL RELATED SEIZURES.
Journal Title: IJAR-Indian Journal of Applied Research - Year 2018, Vol 8, Issue 12
Abstract
Aim: To study the clinical profile of patients with new onset alcohol related seizures (ARS) Materials and Methods: This was a prospective, hospital based, observational study of 50 consecutive patients without a prior diagnosis of epilepsy presenting with seizures related to alcohol intake, to either emergency room or out-patient department, Department of General Medicine, SVS Medical College, Mahabubnagar, Telangana state, between October 2015 to September 2017. An informed and written consent was taken from the patient or immediate responsible attendant. Detailed history including the personal and family history was obtained from all patients. AUDIT scoring was done in all patients. Detailed examination findings were noted down. EEG and CT Scan Brain was done in all patients. MRI Brain was done when required. Results: A total of 50 patients with alcohol withdrawal seizures were included in the study of which 24(48%) were males and 26(32%) were females. Majority of the patients presented with seizures within 6 days following the last bout of alcohol (85%). All the 50(100%) patients presented with generalized tonic clonic seizures (GTCS) and 8(16%) progressed in to status epilepticus. Withdrawal symptoms were present in 24(48%) patients. Family history of seizures in the first degree relative was present in 4(8%) patients. CT evidence of cortical atrophy was present in 10 (20%) patients. EEG suggestive of seizures was present in 15 (30%) patients. Conclusion: There was a slight female preponderance of alcohol related seizures in this study. Majority presented within 6 days after the last bout of alcohol. All presented with GTCS. EEG and CT Scan Brain reports were normal in majority of the patients.
Authors and Affiliations
Dr. Najma Farheen, Dr. Nishant T
Keywords
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