A Study of Clonidine and Dexmedetomidine as Adjuvant to Epidural Levobupivacaine for Post Operative Analgesia in Infraumbilical Surgeries
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 2
Abstract
Background: Epidural analgesia with adjuvant is the popular method for intra and postoperative pain relief but search for ideal adjuvant for prolonging the duration of postoperative analgesia without any side effect goes on. Aim: This study was conducted to study the onset, extent and duration of sensory and motor block and side effects of clonidine or dexmedetomidine when used as an adjuvant in epidural levobupivacaine. Materials and Methods: 80 patients of ASA status I and II, posted for infraumbilical surgery were randomly allocated into two groups of 40 each. Group I group patients received 18 ml of 0.5% levobupivacaine and clonidine 2mcg/kg in epidural route and Group II group patients received 18 ml of 0.5% levobupivacaine and dexmedetomidine 1.5mcg/kg in epidural route. Itraoperative and postoperative block characteristics as well as hemodynamic parameters were observed and recorded. Results: Dexmedetomidine had an earlier onset and longer duration of sensory and motor block in comparison to clonidine. Sedation scores were statistically significant with dexmedetomidine group in comparison to clonidine group. Conclusion: Dexmedetomidine was a better than clonidine as an adjuvant to levobupivacaine in epidural anaesthesia in total knee replacement.
Authors and Affiliations
Dr Narayan Acharya
Keywords
Related Articles
- EP ID EP273423
- DOI -
- Views 73
- Downloads 0
Role of Ultrafiltration in Peritoneal Dialysis: A Review
With the widespread availability of dialysis, the lives of hundreds of thousands of patients with ESRD have been prolong. Peritoneal Dialysis (PD) is an established modality of renal replacement therapy for patients with...
Study of intestinal parasitic infection among primary school children from a tribal community in Nadia district of West Bengal
Objective: The study was undertaken to find out the rate of intestinal parasitic infection among tribal children and to find out the contributing factors of the infection. Method: A total of 103 students from a primary s...
Analysis of Patterns of Mucosal and Histopathological Changes in Cases of Acute Appendicitis
Acute appendicitis is the most common general surgical emergency. The lifetime risk for appendicitis is 7%, commonly occurring in adolescent and young adults[13] . In England, 42,526 patients underwent appendectomies in...
AgNOR Staining in Prostatic Carcinoma - Comparative study with Bcl-2 and Gleason Score
Introduction: AgNOR, a synonym for silver stained nucleolar organizing regions (NORs) of DNA located on the short ends of acrocentric chromosomes are emphasized in actively proliferating cells. When compared with immunoh...
Spinal Anesthesia versus General Anesthesia for open cholcystectomy: Comparison of PERI-operative and post-operative events
Objective: To study perioperative and postoperative events as well as feasibility, effectiveness, safety of patient and surgeons satisfaction for open cholecystectomy under spinal anesthesia (SA) compared to General Anes...