A study of Co- morbidities in children aged 6 months to 12 years receiving multiple blood transfusions
Journal Title: Pediatric Review: International Journal of Pediatric Research - Year 2017, Vol 4, Issue 6
Abstract
Background: Transfusion of blood and blood products is an established way of treating patients who are deficient in one or more blood component. Aim &objective: Blood transfusion is a vital therapeutic measure which influences the outcome of transfusion dependent subjects. Although survival has increased in these subjects parallel to advances in chemotherapy and chelating, they are more prone to acquiring various co morbidities like transfusion transmitted infection (TTI), transfusion associated adverse event, and iron overload leading to a negative impact on quality and duration of life of the patients. Objective: To assess the consequences of multiple blood transfusions, leading to incidence of co morbidities in recipients. Method: the present study entitled co morbidities in patients receiving multiple transfusions is a descriptive Study and has been carried out in institute during the period of February 2015 to February 2016. Patients receiving multiple blood transfusions were categorized as hemolytic disease and non-hemolytic disease. Patients were screened for transfusion transmitted infection like HIV and HBs Ag, serum ferrites. Result: out of 100 subjects, 86 had hemolytic disease and 14 had non hemolytic disease. The study performed showed that out of 98 total co- morbidities, increased serum ferritin contributed to 67.35%, HIV to 10.20%, HbsAg to 15.31% and 7.14% was contributed by Transfusion Associated Serious Adverse Events (TASAE). Conclusion: Blood transfusion can lead to severe adverse effects which can cause temporary or permanent morbidity.
Authors and Affiliations
Mir Sumsam Ali Khurram, C. N. Prasad
Keywords
Related Articles
- EP ID EP281900
- DOI 10.17511/ijpr.2017.06.05
- Views 140
- Downloads 0
Clinical, Pathological and Imaging findings of Giant AxonalNeuropathy (GAN): report from India with review of literature anddifferential diagnosis
Giant axonal neuropathy is a rare autosomal recessive neuro-degenerative disease with simple clinical clues. We describe an 11 year old boy with progressive difficulty in walking with recurrent falls. On examination he h...
Biophysical profile of blood pressure in urban school children
Background: A Systematic review & meta-analysis revealed that there is ‘Strong evidence for tracking of Blood pressure from childhood to adulthood i.e., the Children in the upper percentile of Blood Pressure levels are m...
Predicting the effectiveness of Test of Infant Motor Performance as an early marker of motor development delay in preterm infants
Objectives: The purpose of this study was to determine the effectiveness of Test of Infant Motor Performance (TIMP) in detecting motor developmental delay in preterm infants.Material and methods: The present study was co...
Erosive esophagitis with transient respiratory distress in newborns: a case report
Isolated esophagitis is very rare in newborn infants at birth, although it may occur a few days or weeks later but is generally associated with gastritis or gastroesophageal reflux, infections or trauma. Respiratory dist...
Spectrum of neonatal surgical emergency- a study in rural area tertiary care center of western U.P
Introduction: Neonatal Intestinal obstruction is commonest surgical cause in emergency, in which rapid intervention is required to prevent undesirable side effect of obstruction that includes death. This study provides s...