A Study of Comparison of Serum Lipid Profile of Women with Pregnancy Induced Hypertension and Normal Pregnancy
Journal Title: Scholars Academic Journal of Biosciences - Year 2014, Vol 2, Issue 11
Abstract
Pregnancy induced hypertension is a major cause of fetomaternal morbidy. Studies have shown alteration of serum lipid metabolism in PIH which occur early and may help predicting PIH. The objective of the study was to compare the serum lipid levels in women with pregnancy induced hypertension and normal pregnancy. Forty women were selected in each group after applying exclusion and inclusion criteria. After a detailed history and clinical examination, routine investigation and lipid profile of all was evaluated and data analyzed. Serum lipid levels in the PIH group was significantly higher compared to normal group. Women with PIH had significantly higher values of total cholesterol (348mg/dl, SD+45), Triglycerides (368 mg/dl, SD +39), LDL (201 mg/dl, SD+ 17)and VLDL (107 mg/dl, SD +11) as compared to normotensive pregnant women, total cholesterol (135mg/dl, SD+ 8.7), Triglycerides(120mg/dl, SD + 20), LDL(83 mg/dl, SD + 4.7)and VLDL(26mg/dl, SD+ 5) with p value of 0.0001. However HDL level is found to be significantly higher (p value < 0.05) in normal group (61 mg/dl, SD 2.81) as compared to PIH group.(34.3 mg/dl, SD 4.3). In conclusion, women with PIH have higher total cholesterol, triglycerides, LDL, VLDL and low HDL levels as compared to normotensive pregnant women. Antenatal screening for serum lipids levels can be useful in early detection of PIH.
Authors and Affiliations
Swati Nayan, Mohan Lal Meena, Nupur Hooja, Andleeb Fatima, Nisha Singh, Sapna Aseri
Keywords
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